TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 71nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 85nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 101nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 152nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 167nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 185nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 204nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 211nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 218nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 231nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 241nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 242nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 274nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 297nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 302nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 366nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 404nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 465nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 522nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 537nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 554nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 604nMAssay Description:Displacement of [125I]PACAP27 from PAC1R expressed in HEK293f cellsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 699nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.31E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.34E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 1.84E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 3.24E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 3.58E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 7.97E+3nMAssay Description:Inhibition of human GFP-fused NPP1 expressed in COS7 cells using pnp-TMP as substrate after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Irreversible inhibition of human steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Irreversible inhibition of human steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells assessed as reduction in transformation of [3H]-E1S to E1 after 2 hrs by l...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of mTOR assessed as inhibition of phosphorylation of 4EBP1 by Lantha-Screen enzyme assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair