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Found 8 Enz. Inhib. hit(s) with Target = 'Steryl-sulfatase' and Ligand = 'BDBM50369432'
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50:  0.0300nMAssay Description:Irreversible inhibition of human steroid sulfatase expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of human placental estrone sulfatase expressed in HEK293 cells using [3H]E1S as substrate incubated for 2 hrs by liquid scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50:  0.150nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]E1S as substrate after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of steroid sulfatase (unknown origin) expressed in HEK293 cells using [3H] E1S as substrate after 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of sulfatase (unknown origin) using [3H]DHEAS as substrate after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50:  1.40nMAssay Description:Compound was tested for its ability to inhibit the transformation of [C14]-DHEAS to DHEA by steroid sulfatase derived from human embryonal kidney cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Chu De Qu£Bec - Research Center

Curated by ChEMBL
LigandPNGBDBM50369432(CHEMBL1627465)
Affinity DataIC50:  30nMAssay Description:Inhibition of estrone sulfatase in human JEG-3 cells using [3H]-estrone sulphate as substrate incubated for 1 hr by liquid scintillation counting met...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed