Affinity DataIC50: 0.00200nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 0.730nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 0.950nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.38nMAssay Description:Inhibition of HDAC8 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC3 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.52nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.54nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
Affinity DataIC50: 3.04nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of CDK9/cyclin T1More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.39nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair