Affinity DataKi: 130nMAssay Description:Inhibition of recombinant HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 1.38nMAssay Description:Inhibition of HDAC8 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human histone deacetylase 8 prepared from 293T cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against histone deacetylase 8 prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of human HDAC8 by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC8 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 196nMAssay Description:Inhibition of human HDAC8 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant HDAC8 using fluor de Lys as substrate preincubated for 5 mins followed by substrate addition measured after 25 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant histone deacetylase 8More data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Inhibition of N terminal hexahistidine-tagged human HDAC8 expressed in Sf9 cells after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+3nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of HDAC8 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.31E+4nMAssay Description:Inhibition of HDAC8 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKd: 490nMAssay Description:To determine the dissociation rate of the inhibitor, 1 µM HDAC8 and 20 µM inhibitor (syringe I) were mixed with 100 µM c-SAHA (syringe...More data for this Ligand-Target Pair
Affinity DataKd: 390nMpH: 7.5Assay Description:A fixed concentration of 1.5 µM was titrated with an increasing concentration of the respective inhibitor in protein storage buffer containing 5...More data for this Ligand-Target Pair