Compile Data Set for Download or QSAR
maximum 50k data
Found 2807 with Last Name = 'blanc' and Initial = 'j'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062937(CHEMBL3397908)
Affinity DataKi:  0.0450nMAssay Description:Displacement of [3H]MPPF from 5HT1A receptor in Sprague-Dawley rat hippocampal membrane fraction incubated for 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  0.0590nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50199865((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  0.0670nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50272031((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  0.0810nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50188534((H-Dmt-Tic-Glu-NH-(CH(2))(5)-CO-Dap(6DMN)-NH(2) | ...)
Affinity DataKi:  0.158nMAssay Description:Displacement of [3H]deltorphin C from rat delta opioid receptor in brain P2 synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50016504((S)-3-(2-{[(S)-2-(2-{2-[2-tert-Butoxycarbonylamino...)
Affinity DataKi:  0.230nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50010044(2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataKi:  0.260nMAssay Description:Binding constant against 5-hydroxytryptamine 2 receptor (in vivo)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataKi:  0.280nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to CCK-8 receptor of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataKi:  0.300nMAssay Description:Potency in displacing [3H]propionyl-Cholecystokinin from mouse brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM21147((3S)-3-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(3S)-3-...)
Affinity DataKi:  0.640nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataKi:  0.690nMAssay Description:Binding constant against 5-hydroxytryptamine 2 receptor (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50016504((S)-3-(2-{[(S)-2-(2-{2-[2-tert-Butoxycarbonylamino...)
Affinity DataKi:  0.930nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig pancreatic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263570(CHEMBL4066422)
Affinity DataKi:  1nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  1.11nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  1.15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263570(CHEMBL4066422)
Affinity DataKi:  1.20nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50095155((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)
Affinity DataKi:  1.45nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50016506(CHEMBL262687 | Sodium; (4-{2-(2-acetylamino-3-carb...)
Affinity DataKi:  1.70nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig pancreatic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50140256(CHEMBL3740223)
Affinity DataKi:  2nMAssay Description:Antagonist activity at human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  2nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263572(CHEMBL4092050)
Affinity DataKi:  2nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130461(4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50272022((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  2.15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263577(CHEMBL4099651)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM210850(US9290467, 20)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50276802(4-OHT | Afimoxifene | TamoGel)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558766(CHEMBL4751065)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM210854(US9290467, 24 | US9290467, 25 | US9290467, 26)
Affinity DataKi:  2.5nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263578(CHEMBL4064172)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50084948(CHEMBL195515 | GW7604)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50204261(CHEMBL3969063)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]-LY459477 from human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50272022((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  2.86nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50272023((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  2.92nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholecystokinin receptor type A(Cavia porcellus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50016503(Boc-Asp-D-Tyr(SO3Na)-Nle-Gly-Trp-Nle-Asp-Phe-NH2 |...)
Affinity DataKi:  3nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50138784((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...)
Affinity DataKi:  3nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor 3 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM210859(US9290467, 29)
Affinity DataKi:  3nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263571(CHEMBL4062591)
Affinity DataKi:  3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50272024((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...)
Affinity DataKi:  3.02nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A(Cavia porcellus)
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50016506(CHEMBL262687 | Sodium; (4-{2-(2-acetylamino-3-carb...)
Affinity DataKi:  3.20nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to CCK-8 receptor of guinea pig pancreatic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxosmithkline Research & Development

Curated by ChEMBL
LigandPNGBDBM50276802(4-OHT | Afimoxifene | TamoGel)
Affinity DataKi:  3.20nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50140258(CHEMBL3740325)
Affinity DataKi:  3.5nMAssay Description:Antagonist activity at human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50499955(CHEMBL3741430)
Affinity DataKi:  3.5nMAssay Description:Antagonist activity at human EP4 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263569(CHEMBL4087751)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria

Curated by ChEMBL
LigandPNGBDBM50558768(CHEMBL4759992)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eth Zurich

Curated by ChEMBL
LigandPNGBDBM50263574(CHEMBL4065847)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 2807 total ) | Next | Last >>
Jump to: