Affinity DataKi: 0.0450nMAssay Description:Displacement of [3H]MPPF from 5HT1A receptor in Sprague-Dawley rat hippocampal membrane fraction incubated for 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 0.0590nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0670nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0810nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Universidad De Santiago De Compostela
Curated by ChEMBL
Universidad De Santiago De Compostela
Curated by ChEMBL
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]deltorphin C from rat delta opioid receptor in brain P2 synaptosomesMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig brainMore data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer
Curated by ChEMBL
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Binding constant against 5-hydroxytryptamine 2 receptor (in vivo)More data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to CCK-8 receptor of guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]DAMGO from mu-opioid receptor expressed in CHOK1 cells after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Mus musculus)
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Potency in displacing [3H]propionyl-Cholecystokinin from mouse brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig brainMore data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(RAT)
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer
Curated by ChEMBL
Centre De Recherches De Vitry Alfortville Rh£Ne-Poulenc Rorer
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Binding constant against 5-hydroxytryptamine 2 receptor (in vitro)More data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig pancreatic membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.11nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Affinity DataKi: 1.45nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig pancreatic membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonist activity at human EP4 receptorMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Binding affinity to human 5HT1F receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.15nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-LY459477 from human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 2.86nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.92nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to Cholecystokinin 8 receptor of guinea pig brainMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Binding affinity of the compound towards metabotropic glutamate receptor 3 was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.02nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SHSY5Y cellsMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:The compound was tested for the inhibition of [3H]-Propionyl specific binding to CCK-8 receptor of guinea pig pancreatic membraneMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Glaxosmithkline Research & Development
Curated by ChEMBL
Glaxosmithkline Research & Development
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Antagonist activity at human EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Antagonist activity at human EP4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair