Compile Data Set for Download or QSAR
maximum 50k data
Found 61 with Last Name = 'brockschnieder' and Initial = 'd'
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554513((5RS)-2-(4-Methylbenzyl)-3-oxo-5-(pyrrolidin-1-ylc...)
Affinity DataIC50:  0.160nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554510((5RS)-7-(Cyclopropylcarbonyl)-2-(4-methylbenzyl)-5...)
Affinity DataIC50:  0.170nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554533((5RS)-2-[(5-Chloropyridin-3-yl)methyl]-5-{[(3S)-3-...)
Affinity DataIC50:  0.200nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554514((5RS)-7-Methyl-2-(4-methylbenzyl)-5-(pyrrolidin-1-...)
Affinity DataIC50:  0.220nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312960(3-[1-(2,3-Difluoro-4-methylbenzyl)-5-fluoro-6-meth...)
Affinity DataIC50:  0.25nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554517((5RS)—N-Cyclopropyl-2-(4-methylbenzyl)-3-oxo-...)
Affinity DataIC50:  0.325nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554517((5RS)—N-Cyclopropyl-2-(4-methylbenzyl)-3-oxo-...)
Affinity DataIC50:  0.350nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554514((5RS)-7-Methyl-2-(4-methylbenzyl)-5-(pyrrolidin-1-...)
Affinity DataIC50:  0.370nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554501(US11337973, Example 5 | tert-Butyl (5RS)-5-{[(3S)-...)
Affinity DataIC50:  0.510nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312961(3-[1-(2,3-Difluoro-4-methylbenzyl)-6-methyl-1H-pyr...)
Affinity DataIC50:  0.650nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554520((5RS)-2-(4-Methylbenzyl)-3-oxo-5-(pyrrolidin-1-ylc...)
Affinity DataIC50:  0.660nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554502((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...)
Affinity DataIC50:  0.670nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554521((5RS)-2-{[3-Chloro-4-(trifluoromethyl)pyridin-2-yl...)
Affinity DataIC50:  0.730nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554522((5RS)—N-(3,4-Dichlorophenyl)-2-(4-methylbenzy...)
Affinity DataIC50:  0.870nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554510((5RS)-7-(Cyclopropylcarbonyl)-2-(4-methylbenzyl)-5...)
Affinity DataIC50:  0.870nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554507((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-7...)
Affinity DataIC50:  0.935nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554497(US11337973, Example 1 | tert-Butyl (5RS)-2-(4-meth...)
Affinity DataIC50:  0.970nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554533((5RS)-2-[(5-Chloropyridin-3-yl)methyl]-5-{[(3S)-3-...)
Affinity DataIC50:  1.20nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554505(US11337973, Example 9 | tert-Butyl (5RS)-5-{[(3S)-...)
Affinity DataIC50:  1.27nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554507((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-7...)
Affinity DataIC50:  1.40nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312944(3-[5-Fluoro-1-(2-fluoro-4-methylbenzyl)-6-methyl-1...)
Affinity DataIC50:  1.5nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554523((5RS)—N-(2,2-Difluoroethyl)-2-(4-methylbenzyl...)
Affinity DataIC50:  1.70nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312945(3-[1-(2-Fluoro-4-methylbenzyl)-6-methyl-1H-pyrazol...)
Affinity DataIC50:  2nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554524((5RS)—N-tert-Butyl-2-(4-methylbenzyl)-3-oxo-5...)
Affinity DataIC50:  2.20nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554525((5RS)-2-{[3-Chloro-4-(trifluoromethyl)pyridin-2-yl...)
Affinity DataIC50:  2.40nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554526((5RS)-7-Isobutyl-2-(4-methylbenzyl)-5-(pyrrolidin-...)
Affinity DataIC50:  2.80nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554506((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...)
Affinity DataIC50:  3nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554498((5RS)-2-(4-Methylbenzyl)-5-(pyrrolidin-1-ylcarbony...)
Affinity DataIC50:  3.05nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554502((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-2...)
Affinity DataIC50:  3.5nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554527((5RS)-7-Cyclobutyl-2-(4-methylbenzyl)-5-(pyrrolidi...)
Affinity DataIC50:  4nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312965(3′-[1-(2,3-Difluoro-4-methylbenzyl)-6-methyl...)
Affinity DataIC50:  4nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554531((5RS)-5-{[(3S)-3-Fluoropyrrolidin-1-yl]carbonyl}-7...)
Affinity DataIC50:  4.20nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312950(3-[1-(4-Chloro-2-fluorobenzyl)-6-methyl-1H-pyrazol...)
Affinity DataIC50:  4.5nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312942(Sodium 3-[1-(2,3-difluorobenzyl)-5-fluoro-6-methyl...)
Affinity DataIC50:  5nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312933( 3-[1-(2,3-Difluorobenzyl)-5-fluoro-6-methyl-1H-py...)
Affinity DataIC50:  5nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554528((5RS)-2-(4-Methylbenzyl)-5-(pyrrolidin-1-ylcarbony...)
Affinity DataIC50:  5.10nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554500((5RS)-2-{[3-Chloro-4-(trifluoromethyl)pyridin-2-yl...)
Affinity DataIC50:  5.15nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554499(US11337973, Example 3 | tert-Butyl (5RS)-2-{[3-chl...)
Affinity DataIC50:  5.45nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312948(3-[1-(4-Chloro-2-fluorobenzyl)-5-fluoro-6-methyl-1...)
Affinity DataIC50:  6nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312958(3-[5-Fluoro-1-(3-fluoro-4-methylbenzyl)-6-methyl-1...)
Affinity DataIC50:  8nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312959(3-[1-(3-Fluoro-4-methylbenzyl)-6-methyl-1H-pyrazol...)
Affinity DataIC50:  10nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312962(3′-[1-(2-Fluoro-4-methylbenzyl)-6-methyl-1H-...)
Affinity DataIC50:  16nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312946(3-[1-(2,4-Difluorobenzyl)-5-fluoro-6-methyl-1H-pyr...)
Affinity DataIC50:  21nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312963(3′-[1-(2,3-Difluorobenzyl)-6-methyl-1H-pyraz...)
Affinity DataIC50:  21nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312952(7,7-Dimethyl-3-[6-methyl-1-(2,3,6-trifluorobenzyl)...)
Affinity DataIC50:  21nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312957(3-[1-(2,6-Difluorobenzyl)-6-methyl-1H-pyrazolo[3,4...)
Affinity DataIC50:  24nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312951(3-[5-Fluoro-6-methyl-1-(2,3,6-trifluorobenzyl)-1H-...)
Affinity DataIC50:  27nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312947(3-[1-(2,4-Difluorobenzyl)-6-methyl-1H-pyrazolo[3,4...)
Affinity DataIC50:  34nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM312953(3-[1-(3-Chloro-2-fluorobenzyl)-5-fluoro-6-methyl-1...)
Affinity DataIC50:  42nMAssay Description:To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM554532(US11337973, Example 37 | [(5-Chloropyridin-3-yl)me...)
Affinity DataIC50:  47nMAssay Description:To recombinant full-length human prolyl endopeptidase (PREP, R&D-Systems, 4308-SE; final concentration, for example, 0.4 nM, volume: 25 al) in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 61 total ) | Next | Last >>
Jump to: