Found 1789 with Last Name = 'brubaker' and Initial = 'jd' TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.0500nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.0600nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.0700nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.0700nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.0800nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.0800nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.0900nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.0900nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.100nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 0.100nMAssay Description:Inhibition of N-terminal GST tagged recombinant human EGFR L858R/T790M (669 to end residues) double mutant expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
3D Structure (crystal)TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.100nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.100nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.100nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.100nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.110nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.110nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.110nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.110nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.110nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.110nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.120nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.120nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.120nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.120nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.130nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.130nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.130nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.140nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.140nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.140nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.140nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.140nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.150nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.150nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.150nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.160nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.160nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.160nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.160nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.160nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.170nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.170nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.180nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.180nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.180nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.180nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.180nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.190nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.190nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines
US Patent
Blueprint Medicines
US Patent
Affinity DataIC50: 0.190nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
