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Found 1 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 1' and Ligand = 'BDBM587419'
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Blueprint Medicines

US Patent
LigandPNGBDBM587419(US11534441, Compound 129)
Affinity DataIC50:  0.110nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent