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Found 96 with Last Name = 'bryan' and Initial = 'wm'
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50452590(CHEMBL3084309)
Affinity DataKi:  0.940nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  1.5nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016752(CHEMBL339943 | N*1*-[1-(1-Carbamoyl-4-guanidino-bu...)
Affinity DataKi:  1.5nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016829(10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-1...)
Affinity DataKi:  2.30nMAssay Description:The compound was tested for the ability to displace delta-receptor specific radioligand [3H]DSLETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016829(10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-1...)
Affinity DataKi:  2.30nMAssay Description:The compound was tested for the ability to displace opioid receptor delta specific radioligand [3H]-DSLETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  2.5nMAssay Description:The compound was tested for the ability to displace delta-receptor specific radioligand [3H]DSLETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016752(CHEMBL339943 | N*1*-[1-(1-Carbamoyl-4-guanidino-bu...)
Affinity DataKi:  2.90nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016760(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  3.30nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50452590(CHEMBL3084309)
Affinity DataKi:  3.30nMAssay Description:The compound was tested for the ability to displace delta-receptor specific radioligand [3H]DSLETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016830(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  3.5nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016756(CHEMBL265591 | c(Pmp-D-Tyr(Et)-Phe-Val-Asn-Cys)-Pr...)
Affinity DataKi:  3.70nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016753(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.20nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016753(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.20nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016757(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016757(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020655(CHEMBL408474 | [6-Amino-2-({1-[19-amino-13-benzyl-...)
Affinity DataKi:  4.60nMAssay Description:Compound was tested for inhibition of hog kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020655(CHEMBL408474 | [6-Amino-2-({1-[19-amino-13-benzyl-...)
Affinity DataKi:  4.60nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016747(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.70nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016747(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016833(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  5.40nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016833(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  5.40nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016760(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  5.80nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016760(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  5.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016756(CHEMBL265591 | c(Pmp-D-Tyr(Et)-Phe-Val-Asn-Cys)-Pr...)
Affinity DataKi:  6nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020653(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  6.40nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016755(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  6.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016755(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  6.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016763(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  7.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016763(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  7.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016754(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  8.30nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020656(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  9.40nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020656(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  9.40nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016761(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  9.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  9.40nMAssay Description:The compound was tested for the ability to displace Opioid receptor mu 1 specific radioligand [3H]DAGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020701(1-(13,16-Dibenzyl-7-carbamoylmethyl-10-isopropyl-6...)
Affinity DataKi:  10nMAssay Description:Inhibition of LVP-sensitive adenylate cyclase in a pig renal medullary preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016762(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  11nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016750(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  11nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020654(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  12nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020653(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  12nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020654(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  12nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016834(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  12nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]naloxoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50452590(CHEMBL3084309)
Affinity DataKi:  14nMAssay Description:The compound was tested for the ability to displace Opioid receptor mu 1 specific radioligand [3H]DAGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016832(19-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-1...)
Affinity DataKi:  15nMAssay Description:The compound was tested for the ability to displace receptor specific radioligand [3H]DPDPEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020651(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  19nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020651(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  19nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016829(10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-1...)
Affinity DataKi:  21nMAssay Description:The compound was tested for the ability to displace mu-receptor specific radioligand [3H]DAGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016830(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataKi:  22nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]naloxoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016760(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  26nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Smith Kline And French Laboratories

Curated by ChEMBL
LigandPNGBDBM50452589(CHEMBL2370362)
Affinity DataKi:  26nMAssay Description:The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016749(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  27nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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