Found 491 with Last Name = 'buckheit' and Initial = 'rw' 
Affinity DataIC50: <1nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 using poly(rC)-oligo)dG) as templateMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
Nci-Fcrdc
Nci-Fcrdc
Affinity DataIC50: 7.30nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University
Purdue University
Affinity DataIC50: 16nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase measured as inhibition of incorporation of [32P]GTP in rCDG primerMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of HIV1 reverse transcriptase p66/p51 using poly(rC)-oligo)dG) as templateMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 22.3nMAssay Description:Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Imquest Biosciences
Curated by ChEMBL
Imquest Biosciences
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase activityMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University
Purdue University
Affinity DataIC50: 74nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of PDE4B2 expressed in COS7 cells assessed as cAMP hydrolysisMore data for this Ligand-Target Pair
3D Structure (crystal)TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
Nci-Fcrdc
Nci-Fcrdc
Affinity DataIC50: 110nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 128nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 129nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 137nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 137nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
Affinity DataIC50: 147nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase assessed as 32P-labeled GMP incorporation into nascent DNA strandMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.More data for this Ligand-Target Pair
