TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human PDE4A4 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human PDE4A4 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.590nMAssay Description:Inhibition of human PDE4A4 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.690nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human PDE4B1 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human PDE4A4 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human PDE4D3 assessed as inhibition of [3H]cAMP hydrolysis to [3H]AMP after 15 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
RhôNe-Poulenc Rorer
Curated by ChEMBL
RhôNe-Poulenc Rorer
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair