Affinity DataKi: 0.00300nMAssay Description:Binding affinity at cloned human adenosine A3 receptor expressed in HEK-293 cells was determined using [125I]-AB-MECA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.0310nMAssay Description:Binding affinity at cloned human adenosine A3 receptor expressed in HEK-293 cells was determined using [125I]-AB-MECA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of [125I]OXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]OXY from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]OXY from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity to human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [125I]OXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Affinity DataKi: 0.362nMAssay Description:Binding affinity at cloned human adenosine A3 receptor expressed in HEK-293 cells was determined using [125I]-AB-MECA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.468nMAssay Description:Binding affinity at cloned human adenosine A3 receptor expressed in HEK-293 cells was determined using [125I]-AB-MECA as radioligandMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.586nMAssay Description:Binding affinity at cloned human adenosine A3 receptor expressed in HEK-293 cells was determined using [125I]-AB-MECA as radioligandMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 0.610nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Binding affinity to human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Displacement of [125I]OXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor.More data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Binding affinity at cloned human adenosine A3 receptor expressed in HEK-293 cells was determined using [125I]-AB-MECA as radioligandMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nM ΔG°: -48.4kJ/molepH: 7.4 T: 2°CAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.980nMAssay Description:Binding affinity to human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataKi: 1.13nMAssay Description:Binding affinity was determined in radioligand binding assay at rat striatal Adenosine A2A receptor vs [3H]-CGS- 21680More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataKi: 1.15nMAssay Description:Binding affinity was determined in radioligand binding assay at rat striatal Adenosine A2A receptor vs [3H]-CGS- 21680More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of LVP stimulated adenylate cyclase activity in pig kidney medullary membraneMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataKi: 1.38nMAssay Description:Binding affinity was determined in radioligand binding assay at rat striatal Adenosine A2A receptor vs [3H]-CGS- 21680More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Roche Bioscience
Curated by PDSP Ki Database
Roche Bioscience
Curated by PDSP Ki Database
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division
Curated by ChEMBL
Research And Development Division
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Leiden/Amsterdam Center For Drug Research
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair