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Found 168 with Last Name = 'cherel' and Initial = 'l'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50187686(CHEMBL3828074 | US10526329, Compound 2 | US1107261...)
Affinity DataKi:  15nMAssay Description:Competitive inhibition of human ATX using LPC (16:0) as substrate after 30 mins by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257775(CHEMBL4100462)
Affinity DataIC50:  2nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257807(CHEMBL4073638)
Affinity DataIC50:  5nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257776(CHEMBL4084005)
Affinity DataIC50:  8nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257813(CHEMBL4062291)
Affinity DataIC50:  9nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032334(CHEMBL3353541)
Affinity DataIC50:  9nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM193000(US10526329, Compound 180 | US11072611, Compound 18...)
Affinity DataIC50:  12nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM192946(US11072611, Compound 141 | US9670204, 141 2-((2-et...)
Affinity DataIC50:  22nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM192946(US11072611, Compound 141 | US9670204, 141 2-((2-et...)
Affinity DataIC50:  22nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in LPA 18:2 production after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032340(CHEMBL3353514)
Affinity DataIC50:  25nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM192943(US10526329, Compound 139 | US9670204, 138 2-((2-et...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human ATX using LPC (16:0) as substrate after 30 mins by horseradish peroxidase/choline oxidase coupled enzyme based spectrophotometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM192946(US11072611, Compound 141 | US9670204, 141 2-((2-et...)
Affinity DataIC50:  27nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM192946(US11072611, Compound 141 | US9670204, 141 2-((2-et...)
Affinity DataIC50:  27nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM192946(US11072611, Compound 141 | US9670204, 141 2-((2-et...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human ATX using LPC (16:0) as substrate after 30 mins by horseradish peroxidase/choline oxidase coupled enzyme based spectrophotometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032302(CHEMBL3353483)
Affinity DataIC50:  36nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032437(CHEMBL3353533)
Affinity DataIC50:  36nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032438(CHEMBL3353534)
Affinity DataIC50:  40nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032300(CHEMBL3353485)
Affinity DataIC50:  42nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032305(CHEMBL3353480)
Affinity DataIC50:  44nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032378(CHEMBL3353532)
Affinity DataIC50:  48nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032375(CHEMBL3353530)
Affinity DataIC50:  57nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM354359(2-((2-ethyl-6-(4-(2- (3-hydroxyazetidin- 1-yl)-2- ...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human ATX using LPC (16:0) as substrate after 30 mins by horseradish peroxidase/choline oxidase coupled enzyme based spectrophotometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032337(CHEMBL3353511)
Affinity DataIC50:  63nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032341(CHEMBL3353515)
Affinity DataIC50:  63nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032326(CHEMBL3353475)
Affinity DataIC50:  76nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032330(CHEMBL3353479)
Affinity DataIC50:  76nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032370(CHEMBL3353526)
Affinity DataIC50:  85nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM192616(US10526329, Compound 115 | US11072611, Compound 11...)
Affinity DataIC50:  86nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032442(CHEMBL3353538)
Affinity DataIC50:  90nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032439(CHEMBL3353535)
Affinity DataIC50:  95nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM354335(2-((2-ethyl-6-(4-(2- (3-hydroxyazetidin- 1-yl)-2- ...)
Affinity DataIC50:  102nMAssay Description:Inhibition of human ATX using LPC (16:0) as substrate after 30 mins by horseradish peroxidase/choline oxidase coupled enzyme based spectrophotometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50266529(CHEMBL4091174)
Affinity DataIC50:  103nMAssay Description:Inhibition of human ATX using LPC (16:0) as substrate after 30 mins by horseradish peroxidase/choline oxidase coupled enzyme based spectrophotometric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM192616(US10526329, Compound 115 | US11072611, Compound 11...)
Affinity DataIC50:  115nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032342(CHEMBL3353516)
Affinity DataIC50:  115nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032443(CHEMBL3353539)
Affinity DataIC50:  116nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032279(CHEMBL3353502)
Affinity DataIC50:  118nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50257794(CHEMBL4084750)
Affinity DataIC50:  122nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032319(CHEMBL3353468)
Affinity DataIC50:  123nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM192268(US10526329, Compound 96 | US11072611, Compound 96 ...)
Affinity DataIC50:  126nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032343(CHEMBL3353517)
Affinity DataIC50:  130nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50187686(CHEMBL3828074 | US10526329, Compound 2 | US1107261...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human ATX using LPC (16:0) as substrate after 30 mins by horseradish peroxidase/choline oxidase coupled enzyme based spectrophotometric...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM192922(US10526329, Compound 136 | US11072611, Compound 13...)
Affinity DataIC50:  138nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032444(CHEMBL3353540)
Affinity DataIC50:  138nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032285(CHEMBL3353498)
Affinity DataIC50:  142nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032317(CHEMBL3353466)
Affinity DataIC50:  143nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032373(CHEMBL3353528)
Affinity DataIC50:  156nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032322(CHEMBL3353471)
Affinity DataIC50:  158nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032278(CHEMBL3353503)
Affinity DataIC50:  166nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50032349(CHEMBL3353523)
Affinity DataIC50:  179nMAssay Description:Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM354549(6-((2-ethyl-6-(1-(2- (3-hydroxyazetidin- 1-yl)-2- ...)
Affinity DataIC50:  192nMAssay Description:Inhibition of human ATX using LPC (16:0) as substrate after 30 mins by horseradish peroxidase/choline oxidase coupled enzyme based spectrophotometric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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