Affinity DataKi: 27nMAssay Description:Compound was evaluated for its binding affinity towards muscarinic acetylcholine receptor M2 in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Compound was evaluated for its binding affinity towards muscarinic acetylcholine receptor M2 in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 196nMAssay Description:Compound was evaluated for its binding affinity towards muscarinic acetylcholine receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 636nMAssay Description:Compound was evaluated for its binding affinity towards M2 receptor in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 813nMAssay Description:Compound was evaluated for its binding affinity towards muscarinic acetylcholine receptor M2 in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 926nMAssay Description:Compound was evaluated for its binding affinity towards Muscarinic acetylcholine receptor M2 in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Compound was evaluated for its binding affinity towards M1 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 2.25E+3nMAssay Description:Compound was evaluated for its binding affinity towards muscarinic acetylcholine receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 2.46E+3nMAssay Description:Compound was evaluated for its binding affinity towards M2 receptor in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 2.69E+3nMAssay Description:Compound was evaluated for its binding affinity towards muscarinic acetylcholine receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 3.03E+3nMAssay Description:Compound was evaluated for its binding affinity towards M1 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 3.07E+3nMAssay Description:Compound was evaluated for its binding affinity towards M1 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 3.66E+3nMAssay Description:Compound was evaluated for its binding affinity towards M2 receptor in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 5.38E+3nMAssay Description:Compound was evaluated for its binding affinity towards M1 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 5.46E+3nMAssay Description:Compound was evaluated for its binding affinity towards M1 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 5.64E+3nMAssay Description:Compound was evaluated for its binding affinity towards M2 receptor in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 5.86E+3nMAssay Description:Compound was evaluated for its binding affinity towards M2 receptor in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 7.06E+3nMAssay Description:Compound was evaluated for its binding affinity towards M2 receptor in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 1.05E+4nMAssay Description:Compound was evaluated for its binding affinity towards M1 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.08E+4nMAssay Description:Compound was evaluated for its binding affinity towards M2 receptor in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 1.58E+4nMAssay Description:Compound was evaluated for its binding affinity towards M2 receptor in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 1.59E+4nMAssay Description:Compound was evaluated for its binding affinity towards Muscarinic acetylcholine receptor M1 in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 2.76E+4nMAssay Description:Compound was evaluated for its binding affinity towards M1 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 3.81E+4nMAssay Description:Compound was evaluated for its binding affinity towards muscarinic acetylcholine receptor M2 in rat brainstemMore data for this Ligand-Target Pair
Affinity DataKi: 4.05E+4nMAssay Description:Compound was evaluated for its binding affinity towards M1 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 6.55E+4nMAssay Description:Compound was evaluated for its binding affinity towards muscarinic acetylcholine receptor in rat cortexMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science And Technology
Curated by ChEMBL
Korea Institute Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of BRAF V600E mutantMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: <100nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
Affinity DataEC50: 750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair