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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50005854
Substrate
n/a
Meas. Tech.
ChEMBL_138959 (CHEMBL742771)
Ki
2250±n/a nM
Citation
 Garvey, DS; Wasicak, JT; Chung, JY; Shue, YK; Carrera, GM; May, PD; McKinney, MM; Anderson, D; Cadman, E; Vella-Rountree, L Synthesis and in vitro characterization of novel amino terminally modified oxotremorine derivatives for brain muscarinic receptors. J Med Chem 35:1550-7 (1992) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51390.46
Organism:
RAT
Description:
P08482
Residue:
460
Sequence:
MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50005854
Synonyms:
1-(4-Azetidin-1-yl-but-2-ynyl)-pyrrolidin-2-one | CHEMBL38441
Type:
Small organic molecule
Emp. Form.:
C11H16N2O
Mol. Mass.:
192.2575
SMILES:
O=C1CCCN1CC#CCN1CCC1
Structure:
Search PDB for entries with ligand similarity: