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Found 219 with Last Name = 'clement' and Initial = 'b'
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM23916(3-amidinophenylalanine deriv., 12 | 3-amino-N-(3-{...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257511((S)-methyl 4-(1-(2-(3-(3-aminopropanamido)phenylsu...)
Affinity DataKi:  6.10nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257512((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104914(CHEMBL507322 | US8569313, Inhibitor 26)
Affinity DataKi:  7.5nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257557((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...)
Affinity DataKi:  12nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104911(CHEMBL493116 | US8569313, Inhibitor 23)
Affinity DataKi:  13nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257666((S)-3-amino-N-(3-(N-(1-(4-benzylpiperidin-1-yl)-3-...)
Affinity DataKi:  17nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104912(CHEMBL493936 | US8569313, Inhibitor 24)
Affinity DataKi:  31nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257663((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)
Affinity DataKi:  33nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257664((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)
Affinity DataKi:  37nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257665((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...)
Affinity DataKi:  53nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257667((S)-4-(4-(2-(3-(3-aminopropanamido)phenylsulfonami...)
Affinity DataKi:  53nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104913(CHEMBL523865 | US8569313, Inhibitor 25)
Affinity DataKi:  65nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257761((R)-methyl 1-((S)-2-(3-(3-aminopropanamido)phenyls...)
Affinity DataKi:  100nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257761((R)-methyl 1-((S)-2-(3-(3-aminopropanamido)phenyls...)
Affinity DataKi:  100nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257665((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...)
Affinity DataKi:  110nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257706((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...)
Affinity DataKi:  150nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257707((R)-1-((S)-2-(3-(3-aminopropanamido)phenylsulfonam...)
Affinity DataKi:  180nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257510((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...)
Affinity DataKi:  255nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257663((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)
Affinity DataKi:  270nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257666((S)-3-amino-N-(3-(N-(1-(4-benzylpiperidin-1-yl)-3-...)
Affinity DataKi:  350nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257760(3-amino-N-(3-(N-((2S)-3-(3-carbamimidoylphenyl)-1-...)
Affinity DataKi:  395nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257760(3-amino-N-(3-(N-((2S)-3-(3-carbamimidoylphenyl)-1-...)
Affinity DataKi:  470nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257511((S)-methyl 4-(1-(2-(3-(3-aminopropanamido)phenylsu...)
Affinity DataKi:  600nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257557((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...)
Affinity DataKi:  670nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257512((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...)
Affinity DataKi:  850nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257664((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)
Affinity DataKi:  880nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519933(CHEMBL4444007)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104911(CHEMBL493116 | US8569313, Inhibitor 23)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104911(CHEMBL493116 | US8569313, Inhibitor 23)
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50519934(CHEMBL4461206)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104914(CHEMBL507322 | US8569313, Inhibitor 26)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104912(CHEMBL493936 | US8569313, Inhibitor 24)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104914(CHEMBL507322 | US8569313, Inhibitor 26)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257512((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM23916(3-amidinophenylalanine deriv., 12 | 3-amino-N-(3-{...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM235685(hDDAH inhibitor, 1a)
Affinity DataKi:  2.00E+3nM ΔG°:  -33.8kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-University Kiel

Curated by ChEMBL
LigandPNGBDBM50240715((S)-2-Amino-5-but-3-enimidoylamino-pentanoic acid ...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant human DDAH1 expressed in Escherichia coli BL21 cells using NMMA as substrate measured after 30 mins by colder ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104912(CHEMBL493936 | US8569313, Inhibitor 24)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257664((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257557((S)-4-(1-(2-(3-(3-aminopropanamido)phenylsulfonami...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257666((S)-3-amino-N-(3-(N-(1-(4-benzylpiperidin-1-yl)-3-...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257707((R)-1-((S)-2-(3-(3-aminopropanamido)phenylsulfonam...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257762((S)-methyl 1-((S)-2-(3-(3-aminopropanamido)phenyls...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257706((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM104911(CHEMBL493116 | US8569313, Inhibitor 23)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257706((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-(...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257511((S)-methyl 4-(1-(2-(3-(3-aminopropanamido)phenylsu...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
The Medicines Company (Leipzig)

Curated by ChEMBL
LigandPNGBDBM50257664((S)-3-amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-o...)
Affinity DataKi:  2.56E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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