Affinity DataKi: 0.133nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.640nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.720nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.850nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.970nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 1.62nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 1.68nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 2.42nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 2.59nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 3.49nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Sanofi-Synthelabo Research
Curated by PDSP Ki Database
Sanofi-Synthelabo Research
Curated by PDSP Ki Database
Affinity DataKi: 4.75nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 4.77nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
Sanofi Synthelabo
Curated by PDSP Ki Database
Sanofi Synthelabo
Curated by PDSP Ki Database
Affinity DataKi: 5.10nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Sanofi Synthelabo
Curated by PDSP Ki Database
Sanofi Synthelabo
Curated by PDSP Ki Database
Affinity DataKi: 7.15nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
Sanofi Synthelabo
Curated by PDSP Ki Database
Sanofi Synthelabo
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-5(RAT)
Sanofi Synthelabo
Curated by PDSP Ki Database
Sanofi Synthelabo
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
Sanofi Synthelabo
Curated by PDSP Ki Database
Sanofi Synthelabo
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-5(RAT)
Sanofi Synthelabo
Curated by PDSP Ki Database
Sanofi Synthelabo
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-3(RAT)
Sanofi Synthelabo
Curated by PDSP Ki Database
Sanofi Synthelabo
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Sanofi-Synthelabo Research
Curated by PDSP Ki Database
Sanofi-Synthelabo Research
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Sanofi Synthelabo
Curated by PDSP Ki Database
Sanofi Synthelabo
Curated by PDSP Ki Database
Affinity DataKi: 16nMAssay Description:In vitro inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Sanofi Synthelabo
Curated by PDSP Ki Database
Sanofi Synthelabo
Curated by PDSP Ki Database
Affinity DataKi: 18nMAssay Description:Displacement of [3H]GX-545 from full length human Nav1.7 VSD4 domain expressed in HEK cell membranes measured after 20 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 21.3nMAssay Description:Radioligand-binding assays were performed using the adenosine A3 receptor agonist [125I]-AB-MECA and the A1 receptor agonist [3H]CCPA. Binding assays...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:In vitro inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Concentration of the compound required for classical fast inhibition of cleavage of the chromogenic substrate by human enzyme Coagulation factor X in...More data for this Ligand-Target Pair