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Found 200 with Last Name = 'creason' and Initial = 's'
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50234534(CHEMBL4088945)
Affinity DataIC50:  3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50234536(CHEMBL4065918)
Affinity DataIC50:  10nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50234532(CHEMBL4095951)
Affinity DataIC50:  15nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345406(CHEMBL1784574 | N-(4-tert-Butyl-3-fluorophenyl)-5-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM24400(5-methyl-N-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a...)
Affinity DataIC50:  47nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM24413(JMC521864 Compund DSM2 | N-(anthracen-2-yl)-5-meth...)
Affinity DataIC50:  56nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345441(5-Methyl-N-(5,6,7,8-tetrahydronaphthalen-2yl)-[1,2...)
Affinity DataIC50:  64nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50234535(CHEMBL4097622)
Affinity DataIC50:  70nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50234489(CHEMBL4070447)
Affinity DataIC50:  74nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM28843(N-[3-fluoro-4-(trifluoromethyl)phenyl]-5-methyl-[1...)
Affinity DataIC50:  77nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345420(CHEMBL1784561 | N-(4-tert-Butylphenyl)-5-methyl-[1...)
Affinity DataIC50:  78nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345385(CHEMBL1784580 | N-(Benzo[b]thiophen-5-yl)-5-methyl...)
Affinity DataIC50:  90nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345414(CHEMBL1784567 | N-(4-Pentafluorosulfenylphenyl)-5-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50234533(CHEMBL4080366)
Affinity DataIC50:  144nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345436(5-Chloro-N-(4-trifluoromethyl)phenyl)-[1,2,4]triaz...)
Affinity DataIC50:  170nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50234531(CHEMBL4089012)
Affinity DataIC50:  179nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345442(CHEMBL1784577 | N-(3,5-Difluoro-4-(trifluoromethyl...)
Affinity DataIC50:  190nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345421(CHEMBL600255 | N-(4-isopropylphenyl)-5-methyl-[1,2...)
Affinity DataIC50:  220nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345443(CHEMBL586157 | N-(2,3-Dihydro1H-inden-5-yl)-5-meth...)
Affinity DataIC50:  220nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington At Seattle

LigandPNGBDBM24400(5-methyl-N-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a...)
Affinity DataIC50:  230nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington At Seattle

LigandPNGBDBM28843(N-[3-fluoro-4-(trifluoromethyl)phenyl]-5-methyl-[1...)
Affinity DataIC50:  260nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM28817(5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...)
Affinity DataIC50:  280nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345400(CHEMBL1784556 | N-(4-Butylphenyl)-5-methyl-[1,2,4]...)
Affinity DataIC50:  280nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM28840(N-(3,4-dimethylphenyl)-5-methyl-[1,2,4]triazolo[1,...)
Affinity DataIC50:  350nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington At Seattle

LigandPNGBDBM28817(5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...)
Affinity DataIC50:  380nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345419(CHEMBL1784562 | N-(4-Cyclopropylphenyl)-5-methyl-[...)
Affinity DataIC50:  420nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM28838(N-[4-bromo-3-(trifluoromethyl)phenyl]-5-methyl-[1,...)
Affinity DataIC50:  450nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345387(CHEMBL1784589 | N-(2,3-Dihydro-1H-inden-2-yl)-5-me...)
Affinity DataIC50:  500nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345404(CHEMBL1784576 | N-(3,4-Bis(trifluoromethyl)phenyl)...)
Affinity DataIC50:  540nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345388(5-Methyl-N-(1,2,3,4-tetrahydronaphthalen-2-yl)-[1,...)
Affinity DataIC50:  540nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345405(CHEMBL1784575 | N-(4-Chloro-3-fluorophenyl)-5-meth...)
Affinity DataIC50:  550nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345415(5-Methyl-N-(4-(trifuoromethylthio)phenyl)-[1,2,4]t...)
Affinity DataIC50:  610nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345402(CHEMBL1714424 | N-(4-Ethylphenyl)-5-methyl-[1,2,4]...)
Affinity DataIC50:  610nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345389(CHEMBL1784590 | N-(5-Fluoro-2,3-dihydro-1H-inden-2...)
Affinity DataIC50:  610nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345390(CHEMBL1784594 | N-(6-Fluoro-1,2,3,4-tetrahydronaph...)
Affinity DataIC50:  630nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345391(CHEMBL1784595 | N-(6-Choro-1,2,3,4-tetrahydronapht...)
Affinity DataIC50:  670nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345434(5-Ethyl-N-(4-trifluoromethyl)phenyl-[1,2,4]triazol...)
Affinity DataIC50:  780nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM28815(N-(4-bromophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]p...)
Affinity DataIC50:  780nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345418(CHEMBL1784563 | N-(4-Vinylphenyl)-5-methyl-[1,2,4]...)
Affinity DataIC50:  800nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM28837(N-[4-chloro-3-(trifluoromethyl)phenyl]-5-methyl-[1...)
Affinity DataIC50:  800nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345412(CHEMBL582694 | GNF-Pf-2905 | N1,N1-Dimethyl-N4-(5-...)
Affinity DataIC50:  820nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345399(CHEMBL1784557 | N-(4-Pentylphenyl)-5-methyl-[1,2,4...)
Affinity DataIC50:  820nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM28842(N-(3-fluoro-4-methylphenyl)-5-methyl-[1,2,4]triazo...)
Affinity DataIC50:  860nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345401(CHEMBL1784555 | N-(4-Propylphenyl)-5-methyl-[1,2,4...)
Affinity DataIC50:  990nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345407(2-Methyl-2-(4-(5-methyl-[1,2,4]triazolo[1,5-a]pyri...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345417(CHEMBL1784564 | N-(4-Ethynylphenyl)-5-methyl-[1,2,...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345392(CHEMBL1784591 | N-(5-Bromo-2,3-dihydro-1H-inden-2-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM28819(5-methyl-N-[4-(trifluoromethoxy)phenyl]-[1,2,4]tri...)
Affinity DataIC50:  1.20E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University of Washington At Seattle

LigandPNGBDBM28815(N-(4-bromophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]p...)
Affinity DataIC50:  1.30E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Washington At Seattle

LigandPNGBDBM28810(N-(3-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)
Affinity DataIC50:  1.40E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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