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Found 551 with Last Name = 'emayan' and Initial = 'k'
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81917(BX-2819)
Affinity DataIC50:  0.0400nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81916(lspropyl analog, 5)
Affinity DataIC50:  0.100nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81914(Ethyl carbamate analog, 3)
Affinity DataIC50:  0.100nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81915(Ethyl analog, 4)
Affinity DataIC50:  0.200nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81912(DC23 | Resorcinol analog, 1)
Affinity DataIC50:  0.300nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81913(Unsubstituted phenyl ring analog, 2)
Affinity DataIC50:  0.5nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467209(CHEMBL4291446)
Affinity DataIC50:  23nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467207(CHEMBL4288828)
Affinity DataIC50:  34nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467211(CHEMBL4281179)
Affinity DataIC50:  51nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467212(CHEMBL4285028)
Affinity DataIC50:  79nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467210(CHEMBL4281574)
Affinity DataIC50:  84nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467208(CHEMBL4277939)
Affinity DataIC50:  237nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467214(CHEMBL4277252)
Affinity DataIC50:  360nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467212(CHEMBL4285028)
Affinity DataIC50:  410nMAssay Description:Inhibition of mouse uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467211(CHEMBL4281179)
Affinity DataIC50:  470nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Mus musculus)
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467212(CHEMBL4285028)
Affinity DataIC50:  910nMAssay Description:Inhibition of mouse tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467212(CHEMBL4285028)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467210(CHEMBL4281574)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467212(CHEMBL4285028)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Mus musculus)
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467212(CHEMBL4285028)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of mouse plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467208(CHEMBL4277939)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467209(CHEMBL4291446)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467208(CHEMBL4277939)
Affinity DataIC50:  1.85E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467211(CHEMBL4281179)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467213(CHEMBL4278454)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467209(CHEMBL4291446)
Affinity DataIC50:  3.33E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467214(CHEMBL4277252)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467207(CHEMBL4288828)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467210(CHEMBL4281574)
Affinity DataIC50:  5.45E+3nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467207(CHEMBL4288828)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467215(CHEMBL4290603)
Affinity DataIC50:  7.26E+3nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467215(CHEMBL4290603)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abdulaziz University For Health Sciences

Curated by ChEMBL
LigandPNGBDBM50467215(CHEMBL4290603)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168437(US9675593, 10)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168438(US9675593, 11)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168439(US9675593, 12)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168440(US9675593, 13)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168441(US9675593, 14)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168442(US9675593, 15)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168444(US9675593, 17)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168450(US9675593, 18)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168451(US9675593, 19)
Affinity DataEC50:  1.25E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168452(US9675593, 21)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168453(US9675593, 22)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168454(US9675593, 23)
Affinity DataEC50:  1.25E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168462(US9675593, 24)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168465(US9675593, 25)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168466(US9675593, 26)
Affinity DataEC50: <5.00E+4nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168467(US9675593, 27)
Affinity DataEC50: >2.00E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndothelin-1(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM168468(US9675593, 28)
Affinity DataEC50:  1.25E+5nMAssay Description:Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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