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Found 30 with Last Name = 'foster' and Initial = 'jd'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334215((+/-)-threo-3-Iodomethylphenidate | CHEMBL1641691)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293605(1-(4-aminophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50182555(1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50327148((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293604(1-(4-amino-3-iodophenyl)-2-pyrrolidin-1-yl-pentan-...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293606(1-(4-azio-3-iodophenyl)-2-pyrroldin-1-yl-pentan-1-...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334214((+/-)-threo-N-(p-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataKi:  363nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50048392(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Affinity DataKi:  441nMAssay Description:Displacement of [3H]WIN35428 from human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334212((+/-)-threo-N-(o-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataKi:  517nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334211((+/-)-threo-N-(p-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataKi:  658nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334209((+/-)-threo-N-(o-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334210((+/-)-threo-N-(m-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataKi:  2.06E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334213((+/-)-threo-N-(m-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataKi:  2.75E+3nMAssay Description:Displacement of [3H]WIN-35428 from human DAT stably expressed in mouse N2A cells by scintillation countnigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293605(1-(4-aminophenyl)-2-pyrrolidin-1-yl-pentan-1-one |...)
Affinity DataIC50:  7nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50327148((R)-methyl 2-(4-iodophenyl)-2-((R)-piperidin-2-yl)...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334215((+/-)-threo-3-Iodomethylphenidate | CHEMBL1641691)
Affinity DataIC50:  14nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50182555(1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one ...)
Affinity DataIC50:  32nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50062915(CHEMBL827 | METHYLPHENIDATE | methyl (2R)-phenyl[(...)
Affinity DataIC50:  156nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293604(1-(4-amino-3-iodophenyl)-2-pyrrolidin-1-yl-pentan-...)
Affinity DataIC50:  175nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50293606(1-(4-azio-3-iodophenyl)-2-pyrroldin-1-yl-pentan-1-...)
Affinity DataIC50:  264nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  392nMAssay Description:Displacement of [3H]CFT from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334212((+/-)-threo-N-(o-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50048392(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334211((+/-)-threo-N-(p-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334209((+/-)-threo-N-(o-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334214((+/-)-threo-N-(p-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataIC50:  2.76E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334210((+/-)-threo-N-(m-Azido-benzyl)-3-iodomethylphenida...)
Affinity DataIC50:  4.63E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Duquesne University Mylan School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50334213((+/-)-threo-N-(m-Azido-benzyl)-4-iodomethylphenida...)
Affinity DataIC50:  7.97E+3nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in mouse N2A cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed