Compile Data Set for Download or QSAR
maximum 50k data
Found 930 with Last Name = 'gertsch' and Initial = 'j'
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50180036((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)
Affinity DataKi:  0.0230nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  0.450nM ΔG°:  -54.2kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKi:  0.490nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB1 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50180036((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)
Affinity DataKi:  0.797nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50228072(1,9-dihydroxy-3-(1',1'-dimethylheptyl)-6H-benzo[c]...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKi:  0.830nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50072775(2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...)
Affinity DataKi:  0.890nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50265650(2-(N-(2,5-dimethoxyphenyl)-4-methylphenylsulfonami...)
Affinity DataKi:  1.35nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50605682(CHEMBL5176915)
Affinity DataKi:  1.40nMAssay Description:Competitive inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate assessed as inhibition constant by Michaelis-Menten analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50556542(CHEMBL4780771)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50265648(8-hexyl-3,5,5-trimethyl-2,3,4,5-tetrahydro-1H-chro...)
Affinity DataKi:  1.78nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50265687(CHEMBL496781 | N-(2-ethylphenyl)-2-(5-(2-methoxyph...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cells incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB1 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50180036((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50408224(CHEMBL4164954)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50556533(CHEMBL4781952)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50556533(CHEMBL4781952)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50556531(CHEMBL4779298)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50556534(CHEMBL4760014)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50055571(CHEMBL3329945)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB1 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol | 3',5-...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO cell membranes after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50556534(CHEMBL4760014)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50556535(CHEMBL4782654)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB2R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50408220(CHEMBL4175577)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50265747((4-methylnaphthalen-1-yl)(1-propyl-1H-indol-3-yl)m...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50157304(3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol | 3',5-...)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cell membranes after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50408226(CHEMBL4167303)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50265647((3-methoxynaphthalen-2-yl)(1-pentyl-1H-indol-3-yl)...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM21281((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)
Affinity DataKi:  7.5nM ΔG°:  -47.2kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50222797((2-cyclopentyl-4-(methylsulfonyl)-1,2,3,4-tetrahyd...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50408215(CHEMBL4175177)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50556536(CHEMBL4781965)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]CP55940 from recombinant human CB1R expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  10.6nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO cells incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50562160(CHEMBL4757403)
Affinity DataKi:  11nMAssay Description:Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50222793((4-(ethylsulfonyl)-2-propyl-1,2,3,4-tetrahydropyrr...)
Affinity DataKi:  11.1nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University of Bern

LigandPNGBDBM50408220(CHEMBL4175577)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cell membranes after 90 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50234418((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...)
Affinity DataKi:  12nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50180036((6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetra...)
Affinity DataKi:  13nM ΔG°:  -45.8kJ/molepH: 7.4 T: 2°CAssay Description:In this assay, 18 ug of crude membrane expressing hCB1 or hCB2 receptors were re-suspended in 300 uL of binding buffer containing 50 mM Tris-HCl, 2.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50240608(2-(1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-1H-i...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM21283(3-[(2-iodo-5-nitrophenyl)carbonyl]-1-[(1-methylpip...)
Affinity DataKi:  15.1nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 930 total ) | Next | Last >>
Jump to: