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Found 332 with Last Name = 'gonsiorek' and Initial = 'w'
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329148(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50305990(CHEMBL596388 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329147(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  0.350nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM85739(CHEMBL178372 | JTE-907 | N-(1,3-Benzodioxole-5-ylm...)
Affinity DataKi:  0.380nMAssay Description:Binding affinity for cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329151(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50305989(CHEMBL596387 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50160446(CHEMBL180465 | N-((S)-1-{4-[4-Methoxy-2-(4-methoxy...)
Affinity DataKi:  0.400nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172146(CHEMBL381669 | N-((S)-1-{4-[2-(2-Fluoro-benzenesul...)
Affinity DataKi:  0.400nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329150(1,1,1-trifluoro-N-(1-(1-(1-(2-fluorophenylsulfonyl...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329130((S)-1,1,1-trifluoro-N-(6-(1-(pyridin-2-ylsulfonyl)...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329129(CHEMBL1271093 | N-((4-ethyl-1-(5-fluoro-1-(2-fluor...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172182(CHEMBL371575 | N-((S)-1-{4-[2-(2-Fluoro-benzenesul...)
Affinity DataKi:  0.5nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329144(1,1,1-trifluoro-N-(((3S,4R)-1-(1-(2-fluorophenylsu...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172164(CHEMBL199048 | N-((S)-1-{4-[4-Methoxy-2-(4-methoxy...)
Affinity DataKi:  0.600nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172163(CHEMBL197955 | N-{(S)-1-[4-(2-Benzenesulfonyl-4-me...)
Affinity DataKi:  0.600nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306002(CHEMBL595705 | N-(6-(5-chloro-2-(4-methoxyphenylsu...)
Affinity DataKi:  0.650nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211605((S)-N-(1-(4-(4-chloro-2-(2-fluorophenylsulfonyl)ph...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329159((R)-N-(1-(4-(4-chloro-2-(2-fluorophenylsulfonyl)ph...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329137(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172155(CHEMBL198246 | N-((S)-1-{4-[2-(2-Fluoro-benzenesul...)
Affinity DataKi:  0.900nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172168(CHEMBL370824 | N-((S)-1-{4-[2-(4-Chloro-benzenesul...)
Affinity DataKi:  0.900nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306008(1,1,1-trifluoro-N-(6-(2-(pyridin-2-ylsulfonyl)-5-(...)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329133(1,1,1-trifluoro-N-((1-(1-(pyridin-2-ylsulfonyl)-1H...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329139((S)-1,1,1-trifluoro-N-(6-(1-(2-fluorophenylsulfony...)
Affinity DataKi:  1nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172180(CHEMBL199102 | N-((S)-1-{4-[2-(2-Fluoro-benzenesul...)
Affinity DataKi:  1nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172158((S)-N-(1-(4-(4-chloro-2-(2-fluorophenylsulfonyl)ph...)
Affinity DataKi:  1nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172174(CHEMBL197777 | N-{4-[4-Methoxy-2-(4-methoxy-benzen...)
Affinity DataKi:  1.30nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329135(1,1,1-trifluoro-N-((1-(2-(2-fluorophenylsulfonyl)f...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306017(CHEMBL604704 | N-((1R,5S,6s)-3-(4-chloro-2-(2-fluo...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329143(1,1,1-trifluoro-N-(((3S,4S)-1-(1-(2-fluorophenylsu...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306007(CHEMBL592896 | N-(6-(5-chloro-2-(pyridin-2-ylsulfo...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329128(1,1,1-trifluoro-N-((4-propyl-1-(1-(pyridin-2-ylsul...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306016(CHEMBL596579 | N-(6-(4-chloro-2-(2-fluorophenylsul...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172183(CHEMBL197904 | N-((S)-1-{4-[2-(2,6-Difluoro-benzen...)
Affinity DataKi:  1.80nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329146(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306003(1,1,1-trifluoro-N-(6-(2-(2-fluorophenylsulfonyl)-5...)
Affinity DataKi:  2nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172179(CHEMBL198164 | N-{(S)-1-[4-(2-Benzenesulfonyl-4-ch...)
Affinity DataKi:  2nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329127(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50305993(CHEMBL594300 | N-((1-(4-chloro-2-(2-fluorophenylsu...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297764((R)-5-cyano-3-(3,4-dioxo-2-(1-phenylpropylamino)cy...)
Affinity DataKi:  3nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50306005(1,1,1-trifluoro-N-(6-(2-(2-fluorophenylsulfonyl)-5...)
Affinity DataKi:  3nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329140(CHEMBL1270287 | N-(((3S,4S)-4-ethyl-1-(1-(2-fluoro...)
Affinity DataKi:  3.10nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172175(CHEMBL198251 | N-((S)-1-{4-[2-(3-Fluoro-benzenesul...)
Affinity DataKi:  3.5nMAssay Description:Inhibition constant against Cannabinoid receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297761((R)-6-bromo-3-(3,4-dioxo-2-(1-phenylpropylamino)cy...)
Affinity DataKi:  4nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329141(1,1,1-trifluoro-N-((1-(1-(2-fluorophenylsulfonyl)-...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50329156((R)-1,1,1-trifluoro-N-(1-(4-(2-(2-fluorophenylsulf...)
Affinity DataKi:  4.40nMAssay Description:Inhibition of beta-arrestin binding to recombinant cannabinoid CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50236053((R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataKi:  4.40nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297740((R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1...)
Affinity DataKi:  4.5nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50200887((R)-3-(3,4-dioxo-2-(1-(thiophen-2-yl)propylamino)c...)
Affinity DataKi:  5nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297741((R)-5-cyano-3-(3,4-dioxo-2-(1-(thiophen-2-yl)propy...)
Affinity DataKi:  5nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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