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Found 103 with Last Name = 'greco' and Initial = 'f'
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human CK2alpha' in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human CK2alpha in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  6nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556137(CHEMBL4793819)
Affinity DataIC50:  8nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human DAPK3 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human TBK1 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human FLT3 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556137(CHEMBL4793819)
Affinity DataIC50:  38nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50:  40nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human CLK3 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 3(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant human HIPK3 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of recombinant human PIM1 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  56nMAssay Description:Inhibition of recombinant human CDK1/cyclin B in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556142(CHEMBL4795226)
Affinity DataIC50:  75nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  96nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  163nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072257(2-Benzyl-4-(3,4-dichloro-phenyl)-4-oxo-butyric aci...)
Affinity DataIC50:  180nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072257(2-Benzyl-4-(3,4-dichloro-phenyl)-4-oxo-butyric aci...)
Affinity DataIC50:  180nMAssay Description:Compound was evaluated for inhibition of human recombinant KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50061915(2-Amino-4-(3,4-dichloro-phenyl)-4-oxo-butyric acid...)
Affinity DataIC50:  200nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50061915(2-Amino-4-(3,4-dichloro-phenyl)-4-oxo-butyric acid...)
Affinity DataIC50:  200nMAssay Description:Compound was evaluated for inhibition of human recombinant KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50:  300nMAssay Description:Compound was evaluated for inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556142(CHEMBL4795226)
Affinity DataIC50:  303nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50061915(2-Amino-4-(3,4-dichloro-phenyl)-4-oxo-butyric acid...)
Affinity DataIC50:  330nMAssay Description:Compound was evaluated for the inhibition of rat liver KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072248((S)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyri...)
Affinity DataIC50:  420nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072244((Z)-4-(3,4-Difluoro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50:  440nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072249(4-(3-Chloro-phenyl)-2-hydroxy-4-oxo-butyric acid |...)
Affinity DataIC50:  480nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  552nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T cells measured after 2 hrs by Nano...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha'(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50:  771nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072254((E)-4-(3,4-Dichloro-phenyl)-4-oxo-but-2-enoic acid...)
Affinity DataIC50:  900nMAssay Description:Compound was evaluated for inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072245(4-(3,4-Dichloro-phenyl)-4-oxo-butyric acid | CHEMB...)
Affinity DataIC50:  900nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072260((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50:  950nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072255((E)-4-(3,4-Difluoro-phenyl)-4-oxo-but-2-enoic acid...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072249(4-(3-Chloro-phenyl)-2-hydroxy-4-oxo-butyric acid |...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072244((Z)-4-(3,4-Difluoro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072250(4-(3,4-Dichloro-phenyl)-2-methoxy-4-oxo-butyric ac...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was evaluated for inhibition of rat liver KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072252(4-(3,4-Difluoro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556137(CHEMBL4793819)
Affinity DataIC50:  1.51E+3nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072258(2-Hydroxy-4-(3-nitro-phenyl)-4-oxo-butyric acid | ...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072251(2-Chloro-4-(3,4-dichloro-phenyl)-4-oxo-butyric aci...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072253(4-(3,4-Dichloro-phenyl)-2-methylene-4-oxo-butyric ...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072259((S)-2-Benzyl-4-(3,4-dichloro-phenyl)-4-oxo-butyric...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072257(2-Benzyl-4-(3,4-dichloro-phenyl)-4-oxo-butyric aci...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072252(4-(3,4-Difluoro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50:  3.30E+3nMAssay Description:Compound was evaluated for inhibition of human recombinant KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072247(4-(3,4-Dichloro-phenyl)-2-methyl-4-oxo-butyric aci...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072245(4-(3,4-Dichloro-phenyl)-4-oxo-butyric acid | CHEMB...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072246(4-(3-Fluoro-phenyl)-2-hydroxy-4-oxo-butyric acid |...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of rat brain KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556142(CHEMBL4795226)
Affinity DataIC50:  5.73E+3nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072260((Z)-4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-but-2-...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of rat liver KYN 3-OHase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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