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Found 3 Enz. Inhib. hit(s) with Target = 'Kynurenine 3-monooxygenase' and Ligand = 'BDBM50072242'
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50:  300nMAssay Description:Compound was evaluated for inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was evaluated for inhibition of rat liver KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50072242(4-(3,4-Dichloro-phenyl)-2-hydroxy-4-oxo-butyric ac...)
Affinity DataIC50:  3.30E+3nMAssay Description:Compound was evaluated for inhibition of human recombinant KYN 3-OHaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed