Found 89 with Last Name = 'guo' and Initial = 'a' 
Affinity DataKi: 6nMAssay Description:Displacement of [3H]cyclopamine from wild type Smo expressed in U2OS cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 12.7nMAssay Description:Displacement of [3H]cyclopamine from wild type Smo expressed in U2OS cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 16.2nMAssay Description:Displacement of [3H]cyclopamine from wild type Smo expressed in U2OS cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 37.9nMAssay Description:Displacement of [3H]cyclopamine from wild type Smo expressed in U2OS cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
State University Of New Jersey
Curated by ChEMBL
State University Of New Jersey
Curated by ChEMBL
Affinity DataKi: 4.08E+6nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
State University Of New Jersey
Curated by ChEMBL
State University Of New Jersey
Curated by ChEMBL
Affinity DataKi: 9.10E+6nMAssay Description:TP_TRANSPORTER: inhibition of VACV uptake in PEPT1-expressing CHO cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
State University Of New Jersey
Curated by ChEMBL
State University Of New Jersey
Curated by ChEMBL
Affinity DataKi: 1.28E+7nMAssay Description:TP_TRANSPORTER: inhibition of VACV uptake in PEPT1-expressing CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at Smo in mouse Shh-Light 2 cells assessed as inhibition of Shh-induced Gli1-reporter activity after 2 days by dual-luciferase re...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at Smo in mouse Shh-Light 2 cells assessed as inhibition of Shh-induced Gli1-reporter activity after 2 days by dual-luciferase re...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of FITC-geldanamycin binding to human His-tagged HSP90alpha N-terminal domain (1 to 236 residues) expressed in Escherichia coli BL21star (...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of FITC-geldanamycin binding to human His-tagged HSP90alpha N-terminal domain (1 to 236 residues) expressed in Escherichia coli BL21star (...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 203nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 205nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 234nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 313nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 325nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 393nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of FITC-geldanamycin binding to canine GRP94 incubated for 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 484nMAssay Description:Antagonist activity at Smo in mouse Shh-Light 2 cells assessed as inhibition of Shh-induced Gli1-reporter activity after 2 days by dual-luciferase re...More data for this Ligand-Target Pair
Affinity DataIC50: 519nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 528nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of FITC-geldanamycin binding to canine GRP94 incubated for 5 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 627nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 797nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 914nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 947nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 985nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+3nMAssay Description:Binding affinity to GRP94 N-domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
University Of New South Wales
Curated by ChEMBL
University Of New South Wales
Curated by ChEMBL
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of C-terminal HSP90beta (527 to 724 residues) (unknown origin) interaction with CYP40 measured after 30 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
University Of New South Wales
Curated by ChEMBL
University Of New South Wales
Curated by ChEMBL
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of C-terminal HSP90beta (527 to 724 residues) (unknown origin) interaction with CYP40 measured after 30 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
University Of New South Wales
Curated by ChEMBL
University Of New South Wales
Curated by ChEMBL
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of C-terminal HSP90beta (527 to 724 residues) (unknown origin) interaction with CYP40 measured after 30 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of GST-tagged dog GRP94 (69 to 337 residues) expressed in Escherichia coli BL21 (DE3) measured after 4 hrs by fluorescent polarization ass...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
University Of New South Wales
Curated by ChEMBL
University Of New South Wales
Curated by ChEMBL
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of C-terminal HSP90beta (527 to 724 residues) (unknown origin) interaction with CYP40 measured after 30 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
University Of New South Wales
Curated by ChEMBL
University Of New South Wales
Curated by ChEMBL
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of C-terminal HSP90beta (527 to 724 residues) (unknown origin) interaction with CYP40 measured after 30 mins by AlphaLISA assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
University Of New South Wales
Curated by ChEMBL
University Of New South Wales
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of C-terminal HSP90beta (527 to 724 residues) (unknown origin) interaction with CYP40 measured after 30 mins by AlphaLISA assayMore data for this Ligand-Target Pair
