TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductaseMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against HSV-1 Ribonucleoside diphosphate reductase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductaseMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against HSV-1 Ribonucleoside diphosphate reductase was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against HSV-1 Ribonucleoside diphosphate reductase was determinedMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human CSF1R using poly[Glu:Tyr] (4:1) as substrate incubated for 2 hrs in presence of [33gammaP]ATP by P81 ion exchange chromatographic...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibitory activity against HSV-1 Ribonucleoside diphosphate reductase was determinedMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human His-tagged CSF1R cytoplasmic domain (538 to 910 residues) expressed in baculovirus expression system using fluorescen...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:In vitro inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibitory activity against Escherichia coli leader peptidase using substrate AMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductaseMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory activity was determined against HSV-1 Ribonucleoside diphosphate reductase; value ranges from 36-60 uMMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Integral Biosciences
Curated by ChEMBL
Integral Biosciences
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human c-Kit using poly[Glu:Tyr] (4:1) as substrate measured after 2 hrs in presence of [33gammaP]ATP by P18 ion exchange chromatographi...More data for this Ligand-Target Pair