Compile Data Set for Download or QSAR
maximum 50k data
Found 275 with Last Name = 'hosfield' and Initial = 'dj'
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264020(2-[5-[(4- cyanophenyl)methoxy]pyrazol-1- yl]pyridi...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264012(2-[5-[(4-chloro-2- methoxyphenyl)methoxy]pyrazol- ...)
Affinity DataIC50:  1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264025(2-(4-[2-(dimethylamino)ethyl]- 5-[(4- fluorophenyl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263974(2-(5-(benzyloxy)-1H-pyrazol-1- yl)isonicotinic aci...)
Affinity DataIC50:  1nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263992(2-{5-[(4-bromobenzyl)oxy]-1H- pyrazol-1-yl}pyridin...)
Affinity DataIC50:  2nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM50158627(CHEMBL3787482 | US10023592, Example 81)
Affinity DataIC50:  2nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM191600(2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285038(4-(5-ethylsulfonyl-2-propoxyphenyl)-2-methyl- 6-(1...)
Affinity DataIC50:  2nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263991(2-{5-[(4-ethylbenzyl)oxy]- 1H-pyrazol-1-yl}pyridin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285038(4-(5-ethylsulfonyl-2-propoxyphenyl)-2-methyl- 6-(1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264025(2-(4-[2-(dimethylamino)ethyl]- 5-[(4- fluorophenyl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264001(2-{5-[(4-chloro-2- fluorobenzyl)oxy]-1H-pyrazol-1-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263975(2-{5-[(4-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264021(2-[5-[(4-chloro-2- phenylmethoxyphenyl)methoxy] py...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264020(2-[5-[(4- cyanophenyl)methoxy]pyrazol-1- yl]pyridi...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263978(2-{5-[(4-methoxybenzyl)oxy]-1H- pyrazol-1-yl}pyrid...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50158703(CHEMBL3785832 | US10173996, Example 53 | US9604961...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263990(2-{5-[(4-methylbenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264030(2-[5-[(4-chloro-2- ethoxyphenyl)methoxy]pyrazol-1-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM50158627(CHEMBL3787482 | US10023592, Example 81)
Affinity DataIC50:  5nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285167(2-methyl-6-(1-methylpyrazol-4-yl)-4-(5- methylsulf...)
Affinity DataIC50:  5nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263974(2-(5-(benzyloxy)-1H-pyrazol-1- yl)isonicotinic aci...)
Affinity DataIC50:  5nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263992(2-{5-[(4-bromobenzyl)oxy]-1H- pyrazol-1-yl}pyridin...)
Affinity DataIC50:  6nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM321348(3-({[(1R)-6-methoxy-1,2,3,4- tetrahydronaphthalen-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50:  6nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264003(2-{5-[(4-cyclopropylbenzyl)oxy]- 1H-pyrazol-1-yl}p...)
Affinity DataIC50:  8nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM321334(3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl- methyl...)
Affinity DataIC50:  8nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285166(4-(2-ethoxy-5-methylsulfonylphenyl)-2- methyl-6-(1...)
Affinity DataIC50:  9nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285167(2-methyl-6-(1-methylpyrazol-4-yl)-4-(5- methylsulf...)
Affinity DataIC50:  9nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50:  9nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264012(2-[5-[(4-chloro-2- methoxyphenyl)methoxy]pyrazol- ...)
Affinity DataIC50:  12nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM314142(3-[(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amino]...)
Affinity DataIC50:  12nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM191600(2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50158703(CHEMBL3785832 | US10173996, Example 53 | US9604961...)
Affinity DataIC50:  14nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264020(2-[5-[(4- cyanophenyl)methoxy]pyrazol-1- yl]pyridi...)
Affinity DataIC50:  14nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285034(4-(5-ethylsulfonyl-2-methoxyphenyl)-2- methyl-6-(1...)
Affinity DataIC50:  15nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50457156(CHEMBL4207071)
Affinity DataIC50:  17nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285039(4-[5-ethylsulfonyl-2-(2- hydroxyethoxy)phenyl]-2-m...)
Affinity DataIC50:  18nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264001(2-{5-[(4-chloro-2- fluorobenzyl)oxy]-1H-pyrazol-1-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264030(2-[5-[(4-chloro-2- ethoxyphenyl)methoxy]pyrazol-1-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264025(2-(4-[2-(dimethylamino)ethyl]- 5-[(4- fluorophenyl...)
Affinity DataIC50:  19nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263976(2-{5-[(3-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)
Affinity DataIC50:  22nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264007(2-[4-ethyl-5-[(4- fluorophenyl)methoxy]pyrazol-1- ...)
Affinity DataIC50:  24nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263975(2-{5-[(4-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)
Affinity DataIC50:  24nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

Curated by ChEMBL
LigandPNGBDBM285166(4-(2-ethoxy-5-methylsulfonylphenyl)-2- methyl-6-(1...)
Affinity DataIC50:  24nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264007(2-[4-ethyl-5-[(4- fluorophenyl)methoxy]pyrazol-1- ...)
Affinity DataIC50:  29nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264021(2-[5-[(4-chloro-2- phenylmethoxyphenyl)methoxy] py...)
Affinity DataIC50:  32nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM263990(2-{5-[(4-methylbenzyl)oxy]-1H- pyrazol-1-yl}pyridi...)
Affinity DataIC50:  32nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50:  35nMAssay Description:Inhibition of KDM4C (unknown origin) using biotinylated H3K9me3 peptide and alpha-ketoglutarate as substrate pretreated for 1 hr followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM191600(2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl...)
Affinity DataIC50:  35nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 275 total ) | Next | Last >>
Jump to: