Affinity DataKi: 11nMAssay Description:Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity by displacement of [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate preparation of rat brain without ce...More data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...More data for this Ligand-Target Pair
Affinity DataKi: 617nMAssay Description:Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...More data for this Ligand-Target Pair
Affinity DataKi: 617nMAssay Description:Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...More data for this Ligand-Target Pair
Affinity DataKi: 2.18E+3nMAssay Description:Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...More data for this Ligand-Target Pair
Affinity DataKi: 2.94E+3nMAssay Description:Binding affinity by displacement of [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate preparation of rat brain without ce...More data for this Ligand-Target Pair
Affinity DataKi: 4.70E+3nMAssay Description:Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...More data for this Ligand-Target Pair
Affinity DataKi: 4.70E+3nMAssay Description:Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...More data for this Ligand-Target Pair
Affinity DataKi: 7.40E+3nMAssay Description:Binding affinity by displacement of [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate preparation of rat brain without ce...More data for this Ligand-Target Pair
Affinity DataKi: 7.40E+3nMAssay Description:Binding affinity by displacement of [3H]TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate preparation of rat brain without ce...More data for this Ligand-Target Pair
Affinity DataKi: 3.10E+4nMAssay Description:Binding affinity of the compound was determined by displacement of [3H]-TCP from PCP N-methyl-D-aspartate glutamate receptor of tissue homogenate pre...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Opioid receptor activity in terms of inhibition of [3H]-dihydromorphine binding in rat brain membraneMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Neuroleptic activity in terms of [3H]-spiroperidol binding in rat striatal membraneto Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Opioid activity in terms of inhibition of [3H]-dihydromorphine binding to opioid receptor mu in rat brain membrane.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Opioid activity in terms of inhibition of [3H]-dihydromorphine binding to Opioid receptor mu 1 in rat brain membrane.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Neuroleptic activity in terms of [3H]-spiroperidol binding to dopamine receptor D2 in rat striatal membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Neuroleptic activity in terms of [3H]-spiroperidol binding to Dopamine receptor D2 in rat striatal membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 147nMAssay Description:Neuroleptic activity in terms of [3H]-spiroperidol binding to Dopamine receptor D2 in rat striatal membrane.More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 302nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 302nMAssay Description:Neuroleptic activity in terms of [3H]-spiroperidol binding in rat striatal membrane to Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 598nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.79E+3nMAssay Description:Opioid activity in terms of inhibition of [3H]-dihydromorphine binding to Opioid receptor mu 1 in rat brain membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 3.05E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 3.05E+3nMAssay Description:Neuroleptic activity in terms of [3H]-spiroperidol binding in rat striatal membrane to Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory concentration against rat striatal dopamine (D1) sensitive adenylate cyclase activityMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 3.22E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- spiroperidol to Dopamine receptor D2 in rat striatal membrane preparation by 50%More data for this Ligand-Target Pair
TargetDelta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by ChEMBL
Istituto Superiore Di Sanit£
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%More data for this Ligand-Target Pair