Affinity DataKi: 8.24E+3nM ΔG°: -29.0kJ/molepH: 7.6 T: 2°CAssay Description:Chymotrypsin inhibitory activity of compunds was perfomred by the method of Cannel.More data for this Ligand-Target Pair
Affinity DataKi: 3.18E+4nM ΔG°: -25.7kJ/molepH: 7.6 T: 2°CAssay Description:Chymotrypsin inhibitory activity of compunds was perfomred by the method of Cannel.More data for this Ligand-Target Pair
Affinity DataKi: 4.71E+4nM ΔG°: -24.7kJ/molepH: 7.6 T: 2°CAssay Description:Chymotrypsin inhibitory activity of compunds was perfomred by the method of Cannel.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant LckMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Tyrosine-protein kinase receptor FLT3 (fms-related tyrosine kinase 3) receptorMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Cephalon
Curated by ChEMBL
Cephalon
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Compound was evaluated for inhibitory activity against 20S proteasome from human liver and brainMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2nMAssay Description:Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brainMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 4nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 3More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Government College University
Curated by ChEMBL
Government College University
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brainMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Cephalon
Curated by ChEMBL
Cephalon
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Compound was evaluated for inhibitory activity against 20S proteasome from human liver and brainMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Compound was tested for inhibition of chymotrypsin-like protease of proteasome from postmortem human liver and brainMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 8.32nMAssay Description:Inhibition of mouse COX-2 in LPS-induced mouse peritoneal macrophage assessed as reduction in PGE2 release incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of bee venom phospholipase A2 preincubated for 1 hr followed by addition of phosphotidylcholine and 1-palmitoyl-2-(1-14C) palmitoyl furthe...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity of the compound was evaluated against recombinant human calpain IMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory concentration against human vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair