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Found 6 Enz. Inhib. hit(s) with Target = 'Calpain-1 catalytic subunit' and Ligand = 'BDBM50084655'
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084655(CHEMBL92708 | Calpeptin | Z-Leu-Nle-CHO | [(S)-1-(...)
Affinity DataKi:  7nMAssay Description:The binding affinity against calpain.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084655(CHEMBL92708 | Calpeptin | Z-Leu-Nle-CHO | [(S)-1-(...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity evaluated against recombinant human calpain 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084655(CHEMBL92708 | Calpeptin | Z-Leu-Nle-CHO | [(S)-1-(...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against Calpain 1 in platelets.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084655(CHEMBL92708 | Calpeptin | Z-Leu-Nle-CHO | [(S)-1-(...)
Affinity DataIC50:  52nMAssay Description:Inhibition of calpain (unknown origin) using Suc-LY-AMC as fluorogenic substrate after 60 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084655(CHEMBL92708 | Calpeptin | Z-Leu-Nle-CHO | [(S)-1-(...)
Affinity DataIC50:  297nMAssay Description:Inhibition of human erythrocytes mu-calpain using Pep1 as substrate incubated for 30 mins under shaking condition in presence of CaCl2 by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50084655(CHEMBL92708 | Calpeptin | Z-Leu-Nle-CHO | [(S)-1-(...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against calpain.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed