Found 252 with Last Name = 'kuroha' and Initial = 'm' TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataKi: 82nMAssay Description:Binding affinity to PPARgammaMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of CBP (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 44nMAssay Description:Inhibition of Candida albicans Pkc1 expressed in insect Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of human PKCbeta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of PPARgamma assessed as transcriptional activityMore data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Inhibition of N-terminal His tagged human EP300 (1159-1666 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H4 (1 to 25)-GSGSK p...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human PKCalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CBP (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CBP (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human PKCgamma by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.81E+3nMAssay Description:Inhibition of MYST2 (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Daiichi Sankyo
Curated by ChEMBL
Daiichi Sankyo
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PPARgamma assessed as transcriptional activityMore data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of MYST4 (unknown origin) using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of EP300 in human LK2 cells assessed as reduction in intracellular histone H3 acetylation at lysine 27 residue incubated for 3 hrs by chem...More data for this Ligand-Target Pair
Affinity DataIC50: 3.51E+4nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of GST tagged human TIP60 expressed in Sf9 cells using biotinylated H4 (1 to 25)-GSGSK peptide as substrate incubated for 1 hr by AlphaLIS...More data for this Ligand-Target Pair
Affinity DataIC50: 3.73E+4nMAssay Description:Inhibition of EP300 (unknown origin) by AlphaLISA immunodetection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+4nMAssay Description:Inhibition of GST tagged human PCAF (431 to end residues) expressed in Sf9 cells using biotinylated H3 (1 to 21)-GGK peptide as substrate incubated f...More data for this Ligand-Target Pair
