Found 3659 with Last Name = 'le' and Initial = 'x' TargetMast cell carboxypeptidase A(Rattus norvegicus)
Universitat Aut£Noma De Barcelona
Curated by ChEMBL
Universitat Aut£Noma De Barcelona
Curated by ChEMBL
Affinity DataKi: 0.0170nMAssay Description:Inhibition of rat CPA3 using AAFP as substrate preincubated for 45 mins measured at 30 sec intervals for 15 mins by UV/vis-spectrophotometryMore data for this Ligand-Target Pair
TargetMast cell carboxypeptidase A(Rattus norvegicus)
Universitat Aut£Noma De Barcelona
Curated by ChEMBL
Universitat Aut£Noma De Barcelona
Curated by ChEMBL
Affinity DataKi: 0.0170nMAssay Description:Inhibition of rat CPA3 using AAFP as substrate preincubated for 45 mins measured at 30 sec intervals for 15 mins by UV/vis-spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Inhibition of human CPA1 using AAFP as substrate measured at pre-steady state by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Inhibition of human CPA1 using AAFP as substrate measured at pre-steady state by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.0870nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.0870nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.0890nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.0890nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.107nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.107nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibition of human CPB1 using AAFA as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Inhibition of human CPB1 using AAFA as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.129nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.129nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibition of human CPA1 using AAFP as substrate measured at pre-steady state by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibition of human CPA1 using AAFP as substrate measured at pre-steady state by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Binding affinity for HA-tagged wild type human Adenosine A2A receptor (WT) using [3H]CGS-21680 as radioligand expressed in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human CPA1 using AAFP as substrate measured at pre-steady state by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human CPA1 using AAFP as substrate measured at pre-steady state by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human CPA1 using AAFP as substrate measured at pre-steady state by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human CPA1 using AAFP as substrate measured at pre-steady state by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human CPA2 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human CPA2 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibition of human CPA1 using AAFP as substrate assessed as apparent first-order rate constant measured at pre-steady state by measuring Koff/Kon ra...More data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibition of human CPA1 using AAFP as substrate assessed as apparent first-order rate constant measured at pre-steady state by measuring Koff/Kon ra...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Antagonist activity against PGE2 activated EP1 receptor assessed as ability to inhibit intracellular calcium mobilisation by FLIPRMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of human CPA4 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of human CPA4 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Binding affinity for HA-tagged mutant human Adenosine A2A receptor (H250N) using [3H]-CGS-21,680 as radioligand expressed in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Inhibition of human CPA1 using AAFP as substrate assessed as apparent first-order rate constant measured at pre-steady state by measuring Koff/Kon ra...More data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Inhibition of human CPA1 using AAFP as substrate assessed as apparent first-order rate constant measured at pre-steady state by measuring Koff/Kon ra...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of human CPA1 using AAFP as substrate assessed as apparent first-order rate constant measured at pre-steady state by measuring Koff/Kon ra...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of human CPA1 using AAFP as substrate assessed as apparent first-order rate constant measured at pre-steady state by measuring Koff/Kon ra...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of human CPA1 using AAFP as substrate assessed as apparent first-order rate constant measured at pre-steady state by measuring Koff/Kon ra...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition of human CPA1 using AAFP as substrate assessed as apparent first-order rate constant measured at pre-steady state by measuring Koff/Kon ra...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of human CPA2 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Inhibition of human CPA2 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:In vitro inhibitory activity against human carbonic anhydrase II (hCAII)More data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Binding affinity for HA-tagged mutant human Adenosine A2A receptor (V84L), using [3H]CGS-21680 as radioligand expressed in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human CPA2 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human CPA2 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human CPA1 using AAFP as substrate preincubated for 45 mins to 2 hrs measured at 30 sec intervals for 15 mins by UV/vis-spectrophotomet...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:In vitro inhibitory activity against human carbonic anhydrase II (hCAII)More data for this Ligand-Target Pair
