Affinity DataIC50: 0.400nM EC50: 9.60nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nM EC50: 37nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nM EC50: 30nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nM EC50: 160nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nM EC50: 110nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nM EC50: 2.40nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nM EC50: 26nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human p38betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nM EC50: 140nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of bacterially expressed p38alpha pretreated for 10 mins measured after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nM EC50: 10nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human cloned GST-fused p38alpha expressed in Escherichia coli using myelin basic protein as substrate after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human cloned GST-fused p38alpha expressed in Escherichia coli using myelin basic protein as substrate after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nM EC50: <2nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nM EC50: 61nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of bacterially expressed p38alpha pretreated for 10 mins measured after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nM EC50: 100nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nM EC50: 190nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of bacterially expressed p38alpha pretreated for 10 mins measured after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human cloned GST-fused p38alpha expressed in Escherichia coli using myelin basic protein as substrate after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4nM EC50: 380nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nM EC50: 72nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human cloned GST-fused p38alpha expressed in Escherichia coli using myelin basic protein as substrate after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nM EC50: 69nMpH: 7.5 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nM EC50: 47nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human cloned GST-fused p38alpha expressed in Escherichia coli using myelin basic protein as substrate after 45 minsMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human cloned GST-fused p38alpha expressed in Escherichia coli using myelin basic protein as substrate after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair