Compile Data Set for Download or QSAR
maximum 50k data
Found 769 with Last Name = 'marchand' and Initial = 'p'
TargetProtein kinase C beta type(Homo sapiens (Human))
University College Cork

Curated by ChEMBL
LigandPNGBDBM17055((18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-tr...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of DAG-activated human PKCbeta1 after 10 mins in presence of [32P]ATP by beta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
University College Cork

Curated by ChEMBL
LigandPNGBDBM17055((18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-tr...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of DAG-activated human PKCbeta2 after 10 mins in presence of [32P]ATP by beta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
University College Cork

Curated by ChEMBL
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PKCbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
University College Cork

Curated by ChEMBL
LigandPNGBDBM3175(3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of Wistar rat GSK-3beta using RRAAEELDSRAGS(P)PQL as substrate after 15 mins in presence of [gamma-32P]-ATP by scintillation counting meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Affinity DataIC50:  29nMAssay Description:Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050853(CHEMBL3318029)
Affinity DataIC50:  30nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Sus scrofa)
University College Cork

Curated by ChEMBL
LigandPNGBDBM2605((Arylindolyl)maleimide deriv. 27 | 3-(1-methyl-1H-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of domestic porcine brain full length GSK-3alpha/beta using GS-1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568546(CHEMBL4853288)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
University College Cork

Curated by ChEMBL
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataIC50:  39nMAssay Description:Inhibition of PKCalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50075009(1-Ethyl-5-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...)
Affinity DataIC50:  41nMAssay Description:In vitro inhibition of human Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50075009(1-Ethyl-5-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...)
Affinity DataIC50:  41nMAssay Description:Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50443934(CHEMBL3091797)
Affinity DataIC50:  49nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50075001(4-(3-Imidazol-1-ylmethyl-indol-1-ylmethyl)-benzoni...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of human Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50075003(5-Bromo-1-ethyl-3-[(4-fluoro-phenyl)-imidazol-1-yl...)
Affinity DataIC50:  52nMAssay Description:In vitro inhibition of human Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50075008(1-(2-Chloro-benzyl)-3-imidazol-1-ylmethyl-1H-indol...)
Affinity DataIC50:  54nMAssay Description:In vitro inhibition of human Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50127282(7-[(4-Chloro-phenyl)-imidazol-1-yl-methyl]-1-ethyl...)
Affinity DataIC50:  55nMAssay Description:Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50075004(1-Ethyl-3-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...)
Affinity DataIC50:  57nMAssay Description:In vitro inhibition of human Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50127286(1-Ethyl-7-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...)
Affinity DataIC50:  62nMAssay Description:Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50127279(1-Ethyl-7-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...)
Affinity DataIC50:  62nMAssay Description:In vitro inhibitiion of cytochrome P450 19A1 from human placental microsomes with 2.5 uM [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50127285(5-Chloro-1-ethyl-7-[(4-fluoro-phenyl)-imidazol-1-y...)
Affinity DataIC50:  63nMAssay Description:Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050860(CHEMBL3318034)
Affinity DataIC50:  66nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50127281(7-[(4-Bromo-phenyl)-imidazol-1-yl-methyl]-1-ethyl-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50070528(CHEMBL3408804)
Affinity DataIC50:  71nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50075002(5-Bromo-3-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...)
Affinity DataIC50:  79nMAssay Description:In vitro inhibition of human Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Affinity DataIC50:  80nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University College Cork

Curated by ChEMBL
LigandPNGBDBM2605((Arylindolyl)maleimide deriv. 27 | 3-(1-methyl-1H-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of recombinant full length human CDK9/cyclin T expressed in baculovirus infected Sf9 insect cells using YSPTSPSYSPTSPSYSPTSPSKKKK as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C gamma type(Homo sapiens (Human))
University College Cork

Curated by ChEMBL
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataIC50:  83nMAssay Description:Inhibition of PKCgamma (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050861(CHEMBL3318035)
Affinity DataIC50:  86nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50070560(CHEMBL3408799)
Affinity DataIC50:  88nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50127280(5-Bromo-1-ethyl-7-[(4-fluoro-phenyl)-imidazol-1-yl...)
Affinity DataIC50:  90nMAssay Description:Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University College Cork

Curated by ChEMBL
LigandPNGBDBM2605((Arylindolyl)maleimide deriv. 27 | 3-(1-methyl-1H-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of full length human CDK2/cyclin A using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50070504(CHEMBL3408810)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
University College Cork

Curated by ChEMBL
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataIC50:  110nMAssay Description:Inhibition of PKCepsilon (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50070547(CHEMBL3408802)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50127283(7-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1-ethyl...)
Affinity DataIC50:  110nMAssay Description:Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050858(CHEMBL3318032)
Affinity DataIC50:  112nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Sus scrofa)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463034(CHEMBL4238971)
Affinity DataIC50:  120nMAssay Description:Inhibition of domestic porcine brain full length GSK-3alpha/beta using GS-1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50070553(CHEMBL3408801)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050855(CHEMBL3318008)
Affinity DataIC50:  136nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50568545(CHEMBL4877608)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568544(CHEMBL4870529)
Affinity DataIC50:  160nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50127284(7-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1-ethyl...)
Affinity DataIC50:  170nMAssay Description:Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050852(CHEMBL3318030)
Affinity DataIC50:  171nMAssay Description:Inhibition of Aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50070506(CHEMBL3408808)
Affinity DataIC50:  180nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50568545(CHEMBL4877608)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human CK1 epsilon expressed in baculovirus infected Sf9 cells using RRKHAAIGSpAYSITA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM27437(12-phenyl-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50070529(CHEMBL3408803)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50050854(CHEMBL3318028)
Affinity DataIC50:  191nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Nantes

Curated by ChEMBL
LigandPNGBDBM50127287(5-Bromo-1-ethyl-7-[(4-fluoro-phenyl)-imidazol-1-yl...)
Affinity DataIC50:  200nMAssay Description:Inhibition of cytochrome P450 19A1 of human placental microsomes with [1beta,2beta-3H]testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 769 total ) | Next | Last >>
Jump to: