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Found 55 with Last Name = 'marek' and Initial = 'l'
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human HDAC6 by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424998(CHEMBL2312164)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human HDAC5 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human HDAC5 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239857(CHEMBL4070745)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human HDAC1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50:  12nMAssay Description:Inhibition of human HDAC4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424998(CHEMBL2312164)
Affinity DataIC50:  16nMAssay Description:Inhibition of human HDAC4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424997(CHEMBL2312167)
Affinity DataIC50:  18nMAssay Description:Inhibition of human HDAC6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239859(CHEMBL4088276)
Affinity DataIC50:  25nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424998(CHEMBL2312164)
Affinity DataIC50:  27nMAssay Description:Inhibition of human HDAC6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human HDAC11 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human HDAC2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424997(CHEMBL2312167)
Affinity DataIC50:  33nMAssay Description:Inhibition of human HDAC5 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50:  43nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239856(CHEMBL2311793)
Affinity DataIC50:  52nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239857(CHEMBL4070745)
Affinity DataIC50:  52nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50:  56nMAssay Description:Inhibition of human HDAC6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239859(CHEMBL4088276)
Affinity DataIC50:  77nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424997(CHEMBL2312167)
Affinity DataIC50:  83nMAssay Description:Inhibition of human HDAC4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  108nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 6(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human HDAC6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239856(CHEMBL2311793)
Affinity DataIC50:  189nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  196nMAssay Description:Inhibition of human HDAC8 by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human HDAC1 by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50:  320nMAssay Description:Inhibition of human HDAC1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424997(CHEMBL2312167)
Affinity DataIC50:  320nMAssay Description:Inhibition of human HDAC1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424998(CHEMBL2312164)
Affinity DataIC50:  341nMAssay Description:Inhibition of human HDAC1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239860(CHEMBL4081343)
Affinity DataIC50:  447nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human HDAC11 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424997(CHEMBL2312167)
Affinity DataIC50:  833nMAssay Description:Inhibition of human HDAC8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50:  852nMAssay Description:Inhibition of human HDAC11 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50:  881nMAssay Description:Inhibition of human HDAC2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  920nMAssay Description:Inhibition of human HDAC2 by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424997(CHEMBL2312167)
Affinity DataIC50:  944nMAssay Description:Inhibition of human HDAC2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  960nMAssay Description:Inhibition of human HDAC8 by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424997(CHEMBL2312167)
Affinity DataIC50:  997nMAssay Description:Inhibition of human HDAC11 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424998(CHEMBL2312164)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of human HDAC8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239857(CHEMBL4070745)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239859(CHEMBL4088276)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of human HDAC8 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424998(CHEMBL2312164)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of human HDAC2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50424998(CHEMBL2312164)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of human HDAC11 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  6.16E+3nMAssay Description:Inhibition of human HDAC5 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  8.44E+3nMAssay Description:Inhibition of human HDAC4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239857(CHEMBL4070745)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50239859(CHEMBL4088276)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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