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Found 48 with Last Name = 'maugeais' and Initial = 'c'
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28154(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  13nM EC50:  120nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28138(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  21nM EC50:  430nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28141(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50:  26nM EC50:  360nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28152(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  27nM EC50:  210nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28154(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  29nM EC50:  370nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28142(methyl (2S)-2-[(3-bromobenzene)sulfonyl]-2-[(2R)-7...)
Affinity DataIC50:  30nM EC50:  150nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28137(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  31nM EC50:  1.81E+3nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28141(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50:  49nM EC50:  1.35E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28139(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50:  56nM EC50:  160nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28139(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50:  62nM EC50:  1.07E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28149(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  65nM EC50:  240nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28138(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  73nM EC50:  1.39E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28150(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  83nM EC50:  92nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28142(methyl (2S)-2-[(3-bromobenzene)sulfonyl]-2-[(2R)-7...)
Affinity DataIC50:  100nM EC50:  850nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28137(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  100nM EC50:  2.17E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28155(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  100nM EC50:  160nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28151(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  150nM EC50:  76nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28134(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  150nM EC50:  1.70E+3nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28147((2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H...)
Affinity DataIC50:  170nM EC50:  110nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28152(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  210nM EC50:  1.09E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28150(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  290nM EC50:  430nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28151(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  300nM EC50:  890nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28131(methyl (2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1...)
Affinity DataIC50:  350nM EC50:  250nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28145(methyl (2S)-2-(benzenesulfonyl)-2-[(4R)-11-chloro-...)
Affinity DataIC50:  400nM EC50:  370nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28148(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  490nM EC50:  170nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28143(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50:  500nM EC50:  340nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28135(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  540nM EC50:  2.08E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28140(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50:  700nM EC50:  190nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28135(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  800nM EC50:  1.53E+3nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28134(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  820nM EC50:  2.18E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28149(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  920nM EC50:  1.50E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28131(methyl (2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1...)
Affinity DataIC50:  1.10E+3nM EC50:  1.60E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28140(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50:  1.21E+3nM EC50:  840nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28153(methyl 5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2...)
Affinity DataIC50:  1.63E+3nM EC50:  1.26E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28147((2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H...)
Affinity DataIC50:  1.79E+3nM EC50:  1.09E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28136(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  2.25E+3nM EC50:  2.30E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28148(2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  2.30E+3nM EC50:  770nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28145(methyl (2S)-2-(benzenesulfonyl)-2-[(4R)-11-chloro-...)
Affinity DataIC50:  2.58E+3nM EC50:  4.23E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28146((2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H...)
Affinity DataIC50:  2.70E+3nM EC50:  1.55E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28132(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  3.30E+3nM EC50:  370nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28132(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  3.30E+3nM EC50:  5.81E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28136(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  3.42E+3nM EC50:  3.16E+3nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28146((2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H...)
Affinity DataIC50:  3.87E+3nM EC50:  400nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28144(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50:  3.95E+3nM EC50:  270nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28144(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50:  1.22E+4nM EC50:  2.75E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28143(methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopent...)
Affinity DataIC50:  2.00E+4nM EC50:  1.07E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28133(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  3.12E+4nM EC50: >4.00E+4nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28133(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  8.79E+4nM EC50:  5.80E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed