Affinity DataKi: 0.00212nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00264nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00293nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00300nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00355nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00365nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00400nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataKi: 0.00471nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataKi: 0.00498nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataKi: 0.00530nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00531nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataKi: 0.00545nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00548nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
Affinity DataKi: 0.00581nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataKi: 0.00600nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataKi: 0.00600nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.00642nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataKi: 0.0283nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) isolated from L1210 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.24nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataKi: 6.35nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:In vitro inhibitory activity against L1210 dihydrofolate reductase in rodent neoplastic cellsMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:In vitro inhibitory activity against Dihydrofolate reductase in L1210 cell in miceMore data for this Ligand-Target Pair
Affinity DataIC50: 0nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 0nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 2.64nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 2.78nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 3.52nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus casei.More data for this Ligand-Target Pair
Affinity DataIC50: 3.86nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 5.98nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of Dihydrofolate reductase activity against Lactobacillus casei enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of Dihydrofolate reductase activity against Lactobacillus casei enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of Dihydrofolate reductase activity against Lactobacillus casei enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 15.9nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Evaluated for inhibition of thymidylate synthase (TS) from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) from Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Evaluated for inhibition of dihydrofolate reductase (DHFR) from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Mus musculus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair