Affinity DataIC50: 240nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of mushroom tyrosinase after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of mushroom tyrosinase after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human MMP3 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human MMP1 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of human MMP2 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human MMP1 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human MMP1 catalytic domain by fluorescent substrate assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mushroom tyrosinase after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+5nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.59E+5nMAssay Description:Inhibition of mushroom tyrosinase after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+5nMAssay Description:Inhibition of recombinant anthrax lethal factor after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+5nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+7nMAssay Description:Inhibition of recombinant anthrax lethal factor after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+7nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 981nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 3.10E+3nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 38.1nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 160nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 81.8nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 181nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 284nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 228nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 272nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 285nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 4.53E+3nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals
US Patent
Vertex Pharmaceuticals
US Patent
Affinity DataEC50: 65.9nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair