Affinity DataIC50: 20nMAssay Description:Inhibition of AChE (unknown origin) assessed as inhibition of acetylcholine hydrolysis preincubated for 15 mins by Ellman methodMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced receptor transactivation after 24 hrs by luciferase r...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily B member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily B member 1(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Kv2.1 channel in human INS1 cells assessed as inhibition of outward K+ current by electrophysiology/patch clamp techniqueMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced receptor transactivation after 24 hrs by luciferase r...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced receptor transactivation after 24 hrs by luciferase r...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 8.10E+3nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 2.48E+4nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 2.53E+4nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 3.16E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 4.10E+4nMAssay Description:Antagonist activity at human FXR expressed in HEK293 cells assessed as inhibition of GW4064-induced transactivation after 24 hrs by luciferase report...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
Affinity DataIC50: 5.15E+4nMAssay Description:Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of AChE (unknown origin) assessed as inhibition of acetylcholine hydrolysis preincubated for 15 mins by Ellman methodMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 6.04E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of AChE (unknown origin) assessed as inhibition of acetylcholine hydrolysis preincubated for 15 mins by Ellman methodMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 6.45E+4nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of AChE (unknown origin) assessed as inhibition of acetylcholine hydrolysis preincubated for 15 mins by Ellman methodMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: 8.11E+4nMAssay Description:Antagonist activity against FXR assessed as transactivation of luciferase reporter gene in CV1 cellsMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Daegu-Gyeongbuk Medical Innovation Foundation
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human FXR expressed in monkey CV1 cells after 24 hrs by ecdysone receptor response element-driven luciferase reporter assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 83.1nMAssay Description:Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 15.2nMAssay Description:Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 39.4nMAssay Description:Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 24.6nMAssay Description:Agonist activity at human PPAR-alpha expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 6.20nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 4.5nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 8.5nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human PPAR-gamma expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human PPAR-gamma expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human PPAR-gamma expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair