TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKi: 2.18E+3nMAssay Description:Uncompetitive inhibition of human N-terminal His6-SUMO-tagged SIRT2 catalytic domain (43 to 356 residues) deacetylase activity expressed in Escherich...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Bayreuth
Curated by ChEMBL
University Of Bayreuth
Curated by ChEMBL
Affinity DataKi: 2.22E+3nMAssay Description:Uncompetitive inhibition of human N-terminal His6-SUMO-tagged SIRT2 catalytic domain (43 to 356 residues) deacetylase activity expressed in Escherich...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMT: 2°CAssay Description:Inhibition of human recombinant HDAC6 pre-incubated at room temperature for 15 min before substrate addition by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMT: 2°CAssay Description:Inhibition of human recombinant HDAC6 pre-incubated at room temperature for 15 min before substrate addition by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of full length His-tagged human recombinant HDAC6 expressed in baculovirus system using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant GSK3beta using GSM as substrate incubated for 30 mins by luminescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against maize histone deacetylase 2More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of maize HD2More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of mouse HDAC1More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMT: 2°CAssay Description:Inhibition of human recombinant HDAC6 pre-incubated at room temperature for 15 min before substrate addition by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMT: 2°CAssay Description:Inhibition of human recombinant HDAC6 pre-incubated at room temperature for 15 min before substrate addition by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full length HDAC6 expressed in insect SF9 cells using fluorogenic ZMAL as substrate after 90 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of maize HD1BMore data for this Ligand-Target Pair