Compile Data Set for Download or QSAR
maximum 50k data
Found 42 with Last Name = 'numa' and Initial = 'mm'
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240523(CHEMBL4084630)
Affinity DataIC50:  6.80nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240524(CHEMBL4079603)
Affinity DataIC50:  9.5nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240521(CHEMBL4095348)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240522(CHEMBL4067946)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240505(CHEMBL4077559)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240525(CHEMBL4070911)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240506(CHEMBL4103102)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240518(CHEMBL4103858)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240517(CHEMBL4066107)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240516(CHEMBL4094558)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50030448(8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | CHEMBL269732 ...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240511(CHEMBL4087653)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240519(CHEMBL4091778)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240508(CHEMBL4079773)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240526(CHEMBL4100390)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240515(CHEMBL4084186)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240507(CHEMBL4078827)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at human FKBP12 measured after 30 mins by fluorescein labelled SLF tracer based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240505(CHEMBL4077559)
Affinity DataIC50:  824nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FKBP12 expressed in Escherichia coli assessed as inhibition of FK506 mediated FKBP12 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240516(CHEMBL4094558)
Affinity DataIC50:  850nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FKBP12 expressed in Escherichia coli assessed as inhibition of FK506 mediated FKBP12 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240517(CHEMBL4066107)
Affinity DataIC50:  989nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FKBP12 expressed in Escherichia coli assessed as inhibition of FK506 mediated FKBP12 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240524(CHEMBL4079603)
Affinity DataIC50:  1.08E+3nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FKBP12 expressed in Escherichia coli assessed as inhibition of FK506 mediated FKBP12 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240518(CHEMBL4103858)
Affinity DataIC50:  1.10E+3nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FKBP12 expressed in Escherichia coli assessed as inhibition of FK506 mediated FKBP12 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240525(CHEMBL4070911)
Affinity DataIC50:  1.11E+3nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FKBP12 expressed in Escherichia coli assessed as inhibition of FK506 mediated FKBP12 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240521(CHEMBL4095348)
Affinity DataIC50:  1.29E+3nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FKBP12 expressed in Escherichia coli assessed as inhibition of FK506 mediated FKBP12 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240523(CHEMBL4084630)
Affinity DataIC50:  1.31E+3nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FKBP12 expressed in Escherichia coli assessed as inhibition of FK506 mediated FKBP12 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240522(CHEMBL4067946)
Affinity DataIC50:  1.74E+3nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FKBP12 expressed in Escherichia coli assessed as inhibition of FK506 mediated FKBP12 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Amplyx Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50240506(CHEMBL4103102)
Affinity DataIC50:  1.81E+3nMAssay Description:Antagonist activity at recombinant human N-terminal His6-tagged FKBP12 expressed in Escherichia coli assessed as inhibition of FK506 mediated FKBP12 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281056(US10022352, Compound 317)
Affinity DataEC50:  4.53E+3nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281055(US10022352, Compound 316)
Affinity DataEC50:  285nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281054(US10022352, Compound 315)
Affinity DataEC50:  272nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281053(US10022352, Compound 314)
Affinity DataEC50:  228nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281052(US10022352, Compound 313)
Affinity DataEC50:  284nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281051(US10022352, Compound 312)
Affinity DataEC50:  181nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281050(US10022352, Compound 311)
Affinity DataEC50:  81.8nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281049(US10022352, Compound 310 | US10022352, Compound 31...)
Affinity DataEC50:  160nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281048(US10022352, Compound 309)
Affinity DataEC50:  38.1nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281047(US10022352, Compound 308)
Affinity DataEC50:  3.10E+3nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281046(US10022352, Compound 307)
Affinity DataEC50:  981nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281049(US10022352, Compound 310 | US10022352, Compound 31...)
Affinity DataEC50:  65.9nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281060(US10022352, Compound 321)
Affinity DataEC50:  1.81E+3nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281059(US10022352, Compound 320)
Affinity DataEC50:  4.32E+3nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM281058(US10022352, Compound 319)
Affinity DataEC50:  39.1nMAssay Description:Single-Channel Recordings activity of wt-CFTR and temperature-corrected ΔF508-CFTR expressed in NIH3T3 cells was observed using excised inside-o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent