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Found 168 with Last Name = 'obata' and Initial = 't'
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227045(CHEMBL354129)
Affinity DataIC50:  0.0310nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50023198(8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5...)
Affinity DataIC50:  0.0440nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223276(CHEMBL65426)
Affinity DataIC50:  0.0510nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227075(CHEMBL171021)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223272(CHEMBL67668)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227072(CHEMBL169790)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227054(CHEMBL354530)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227053(CHEMBL170191)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223263(CHEMBL291889)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223346(CHEMBL65114)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227047(CHEMBL172889)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227136(CHEMBL170100)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227144(CHEMBL83797)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223224(CHEMBL65115)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227063(CHEMBL170017)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223948(CHEMBL283443)
Affinity DataIC50:  0.850nMAssay Description:Inhibition of PDE4 from U937 monocytic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227040(CHEMBL312105)
Affinity DataIC50:  0.860nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223341(CHEMBL294494)
Affinity DataIC50:  0.910nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227140(CHEMBL171689)
Affinity DataIC50:  0.960nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223220(CHEMBL63461)
Affinity DataIC50:  1nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227190(CHEMBL171022)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223945(CHEMBL264369)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of PDE4 from U937 monocytic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227060(CHEMBL170959)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227137(CHEMBL422917)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227086(CHEMBL170393)
Affinity DataIC50:  2nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227051(CHEMBL81565)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227041(CHEMBL353429)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223275(CHEMBL64989)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223348(CHEMBL66357)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227064(CHEMBL172766)
Affinity DataIC50:  5nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223369(CHEMBL111171)
Affinity DataIC50:  5nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227098(CHEMBL170506)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227079(CHEMBL83447)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227033(CHEMBL311891)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223344(CHEMBL63568)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223271(CHEMBL63028)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) prepared from human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227074(CHEMBL312051)
Affinity DataIC50:  7nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227036(CHEMBL312090)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227073(CHEMBL80993)
Affinity DataIC50:  9nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223953(CHEMBL27107)
Affinity DataIC50:  9nMAssay Description:Inhibition of PDE4 from U937 monocytic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223950(CHEMBL280611)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of PDE4 from U937 monocytic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223350(CHEMBL107968)
Affinity DataIC50:  10nMAssay Description:Inhibition of phosphodiesterase 4 (PDE4) from U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50326129(Indometacin)
Affinity DataIC50:  10nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50326129(Indometacin)
Affinity DataIC50:  10nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PDE4 from U937 monocytic cellsMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227062(CHEMBL174377)
Affinity DataIC50:  11nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50223955(CHEMBL24839)
Affinity DataIC50:  12nMAssay Description:Inhibition of PDE4 from U937 monocytic cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227065(CHEMBL82033)
Affinity DataIC50:  13nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50227035(CHEMBL311759)
Affinity DataIC50:  14nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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