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Found 400 with Last Name = 'orton' and Initial = 'e'
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090364(3-[2-Hydroxycarbamoyl-1-(4-methoxy-benzenesulfonyl...)
Affinity DataKi:  0.800nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090350(4-Ethyl-3-(4-methoxy-benzenesulfonyl)-octanoic aci...)
Affinity DataKi:  4nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090372(3-(4-Methoxy-benzenesulfonyl)-4-phenyl-pentanoic a...)
Affinity DataKi:  8nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090347(3-Cyclohexyl-N-hydroxy-3-(4-methoxy-benzenesulfony...)
Affinity DataKi:  8nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080367((R)-1-{2-[(Z)-2-(2-Chloro-phenyl)-2-phenyl-vinylox...)
Affinity DataKi:  12nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080358(1-{2-[2,2-Bis-(2-chloro-phenyl)-vinyloxy]-ethyl}-1...)
Affinity DataKi:  12nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080382((R)-1-{2-[(Z)-2-(2-Chloro-phenyl)-2-o-tolyl-vinylo...)
Affinity DataKi:  12nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080337((R)-1-{2-[2,2-Bis-(3-methyl-thiophen-2-yl)-vinylox...)
Affinity DataKi:  14nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080376((R)-1-{2-[(E)-2-(3-Methyl-thiophen-2-yl)-2-o-tolyl...)
Affinity DataKi:  17nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080327(1-{2-[(Z)-2-(2-Fluoro-phenyl)-2-o-tolyl-vinyloxy]-...)
Affinity DataKi:  19nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080335((R)-1-[2-(2,2-Di-o-tolyl-vinyloxy)-ethyl]-piperidi...)
Affinity DataKi:  19nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074027(3-(4-Methoxy-benzenesulfonyl)-7-phenyl-heptanoic a...)
Affinity DataKi:  20nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080375((R)-1-[2-((E)-2-Phenyl-2-o-tolyl-vinyloxy)-ethyl]-...)
Affinity DataKi:  21nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080368(1-[2-(2,2-Di-o-tolyl-vinyloxy)-ethyl]-1,2,5,6-tetr...)
Affinity DataKi:  26nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090377(3-(4-Methoxy-benzenesulfonyl)-5,7,7-trimethyl-octa...)
Affinity DataKi:  27nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080388((R)-1-{2-[(E)-2-(3-Fluoro-phenyl)-2-o-tolyl-vinylo...)
Affinity DataKi:  28nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50089209(3-(4-Methoxy-benzenesulfonyl)-heptanoic acid hydro...)
Affinity DataKi:  30nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080331((R)-1-{2-[(Z)-2-(4-Fluoro-2-methyl-phenyl)-2-o-tol...)
Affinity DataKi:  30nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090366(3-(4-Methoxy-benzenesulfonyl)-nonanoic acid hydrox...)
Affinity DataKi:  31nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080365((R)-1-{2-[1-(2,4-Dichloro-phenyl)-1-(3-methyl-thio...)
Affinity DataKi:  32nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080355((R)-1-{2-[2,2-Bis-(2-ethyl-phenyl)-vinyloxy]-ethyl...)
Affinity DataKi:  32nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090357(5-Cyclohexyl-3-(4-methoxy-benzenesulfonyl)-pentano...)
Affinity DataKi:  36nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090382(4-Benzyloxy-N-hydroxy-3-(4-methoxy-benzenesulfonyl...)
Affinity DataKi:  38nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080328((R)-1-{2-[Bis-(2-chloro-phenyl)-methyleneaminooxy]...)
Affinity DataKi:  39nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080369((S)-1-{2-[Bis-(3-methyl-thiophen-2-yl)-methyleneam...)
Affinity DataKi:  41nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080373((R)-1-{2-[1-(2-Fluoro-phenyl)-1-o-tolyl-meth-(Z)-y...)
Affinity DataKi:  41nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074021(3-(4-Methoxy-benzenesulfonyl)-5-phenyl-pentanoic a...)
Affinity DataKi:  43nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50074028(3-(4-Methoxy-benzenesulfonyl)-6-phenyl-hexanoic ac...)
Affinity DataKi:  44nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080359(1-{2-[2,2-Bis-(2-ethyl-phenyl)-vinyloxy]-ethyl}-1,...)
Affinity DataKi:  47nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080344(1-(2-Benzhydrylideneaminooxy-ethyl)-1,2,5,6-tetrah...)
Affinity DataKi:  47nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080370((R)-1-{2-[(Z)-2-(3-Fluoro-phenyl)-2-o-tolyl-vinylo...)
Affinity DataKi:  48nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080323((R)-1-[2-((Z)-2-Phenyl-2-o-tolyl-vinyloxy)-ethyl]-...)
Affinity DataKi:  49nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080333((R)-1-{2-[(E)-2-(2,4-Difluoro-phenyl)-2-(2,5-diflu...)
Affinity DataKi:  51nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080340((R)-1-{2-[(2,4-Difluoro-phenyl)-(2,5-difluoro-phen...)
Affinity DataKi:  52nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080330((R)-1-{2-[(E)-2-(2-Chloro-phenyl)-2-phenyl-vinylox...)
Affinity DataKi:  52nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080336((R)-1-{2-[2,2-Bis-(2-chloro-phenyl)-vinyloxy]-ethy...)
Affinity DataKi:  52nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080324(1-(2-Di-o-tolylmethyleneaminooxy-ethyl)-1,2,5,6-te...)
Affinity DataKi:  55nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080387((R)-1-{2-[1-(1-Methyl-1H-pyrrol-2-yl)-1-phenyl-met...)
Affinity DataKi:  59nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50090364(3-[2-Hydroxycarbamoyl-1-(4-methoxy-benzenesulfonyl...)
Affinity DataKi:  60nMAssay Description:In vitro inhibition of human recombinant Matrix metalloproteinase-3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080374((R)-1-{2-[2,2-Bis-(4-fluoro-2-methyl-phenyl)-vinyl...)
Affinity DataKi:  61nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080341(1-{2-[(Z)-2-(3-Chloro-phenyl)-2-o-tolyl-vinyloxy]-...)
Affinity DataKi:  64nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080381((R)-1-{2-[2,2-Bis-(2-chloro-4-fluoro-phenyl)-vinyl...)
Affinity DataKi:  66nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50368628(ABT-569 | Abbott-70569 | Abbott-70569.1 | Gabitril...)
Affinity DataKi:  67nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080354((R)-1-{2-[1-(3-Methyl-thiophen-2-yl)-1-o-tolyl-met...)
Affinity DataKi:  70nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080354((R)-1-{2-[1-(3-Methyl-thiophen-2-yl)-1-o-tolyl-met...)
Affinity DataKi:  70nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080364((R)-1-(2-Di-o-tolylmethyleneaminooxy-ethyl)-piperi...)
Affinity DataKi:  71nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080334((R)-1-{2-[1-(3-Methyl-thiophen-2-yl)-1-thiophen-2-...)
Affinity DataKi:  74nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080380(1-{2-[2,2-Bis-(4-fluoro-2-methyl-phenyl)-vinyloxy]...)
Affinity DataKi:  79nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080346((R)-1-(2-Benzhydrylideneaminooxy-ethyl)-piperidine...)
Affinity DataKi:  81nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50080369((S)-1-{2-[Bis-(3-methyl-thiophen-2-yl)-methyleneam...)
Affinity DataKi:  82nMAssay Description:In vitro inhibition of [3H]GABA uptake at the Sodium- and chloride-dependent GABA transporter 1 (GAT-1) uptake site in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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