Affinity DataKi: 0.100nMAssay Description:Competitive binding to PLK4 (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Tested for binding affinity for human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
Affinity DataKi: 0.149nMAssay Description:Inhibitory constant against binding of [125I]- IBZM to rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Tested for binding affinity for human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
Affinity DataKi: 0.203nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Competitive binding to PLK4 (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.302nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.390nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.430nMAssay Description:Tested for binding affinity for human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Tested for binding affinity for human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.633nMAssay Description:Inhibitory constant against binding of [125I]- IBZM to rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Competitive binding to PLK4 (unknown origin) by double reciprocal plot analysis in presence of ATPMore data for this Ligand-Target Pair
Affinity DataKi: 0.780nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]PK11195 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.851nMAssay Description:Inhibitory constant against binding of [125I]- IBZM to rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.860nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.860nMAssay Description:Displacement of [3H]epibatidine from Lymnaea stagnalis acetylcholine-binding protein incubated for 60 mins followed by 3 hrs incubation in dark condi...More data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.884nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.960nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1nMAssay Description:Ser/Thr-kinase selectivity assays were performed using a radioactive FlashPlate-based assay platform. Substrate incorporated radioactivity was counte...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal
Curated by ChEMBL
University Of Kwazulu-Natal
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [125I-Tyr0]-CRF from recombinant human CRF1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.04nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Tested for binding affinity for human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
Affinity DataKi: 1.14nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.16nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair
Affinity DataKi: 1.31nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]Ro5-4864 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.44nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal
Curated by ChEMBL
University Of Kwazulu-Natal
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [125I-Tyr0]-CRF from recombinant human CRF1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity to human CA7 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.52nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.69nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.69nMAssay Description:Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in Sprague-Dawley rat cerebral cortex membrane by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal
Curated by ChEMBL
University Of Kwazulu-Natal
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [125I-Tyr0]-CRF from recombinant human CRF1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovaryMore data for this Ligand-Target Pair