Compile Data Set for Download or QSAR
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Found 349 with Last Name = 'parham' and Initial = 'k'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001019(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011851(2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo...)
Affinity DataKi:  0.270nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403547(ATROPEN | ATROPINE)
Affinity DataKi:  1nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001036(3-(3-Chloro-allyl)-6,11-dimethyl-1,2,3,4,5,6-hexah...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [3H]- 5-HT uptake in Serotonin transporter using serotonin uptake assay in rat midbrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035725(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001039(6,11-Dimethyl-3-(1-methyl-allyl)-1,2,3,4,5,6-hexah...)
Affinity DataKi:  3nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001031(3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-me...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001046(6,11-Dimethyl-3-(4-phenyl-butyl)-1,2,3,4,5,6-hexah...)
Affinity DataKi:  4nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001027(3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]- 5-HT uptake in Serotonin transporter using serotonin uptake assay in rat midbrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001026(3-But-2-ynyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50033127(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035738((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  5.90nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001037(6,11-Dimethyl-3-(1-methyl-allyl)-1,2,3,4,5,6-hexah...)
Affinity DataKi:  5.90nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035726(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataKi:  6nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035752(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035729(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...)
Affinity DataKi:  7nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50010195((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035729(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...)
Affinity DataKi:  8.40nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001021(3-But-2-enyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2...)
Affinity DataKi:  9nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035746(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-ca...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001025(3-But-2-enyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2...)
Affinity DataKi:  11nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001038(6,11-Dimethyl-3-(3-methyl-butyl)-1,2,3,4,5,6-hexah...)
Affinity DataKi:  11nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035725(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  13nMAssay Description:Ratio of Ki value towards Serotonin transporter to that of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001033((-)-Pentazocine | 3-But-2-enyl-6,11-dimethyl-1,2,3...)
Affinity DataKi:  13nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035751(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-ca...)
Affinity DataKi:  15nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035729(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...)
Affinity DataKi:  19nMAssay Description:Inhibition of [3H]- 5-HT uptake in Serotonin transporter using serotonin uptake assay in rat midbrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001052(6,11-Dimethyl-3-(3-phenyl-propyl)-1,2,3,4,5,6-hexa...)
Affinity DataKi:  20nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50451132(CHEMBL2079586 | WIN-35428)
Affinity DataKi:  23nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001020(6,11-Dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-be...)
Affinity DataKi:  23nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50005685(2,2-Diphenyl-propionic acid 2-diethylamino-ethyl e...)
Affinity DataKi:  23nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035752(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  33nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataKi:  37nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50451132(CHEMBL2079586 | WIN-35428)
Affinity DataKi:  39nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035725(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  41nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataKi:  50nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035752(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  52nMAssay Description:Inhibition of [3H]- 5-HT uptake in Serotonin transporter using serotonin uptake assay in rat midbrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001043(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  55nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001050(6,11-Dimethyl-3-(5-phenyl-pentyl)-1,2,3,4,5,6-hexa...)
Affinity DataKi:  68nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035751(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane-2-ca...)
Affinity DataKi:  73nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001029(3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...)
Affinity DataKi:  97nMAssay Description:Binding affinity against opioid receptor mu using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50451132(CHEMBL2079586 | WIN-35428)
Affinity DataKi:  101nMAssay Description:Inhibition of [3H]- 5-HT uptake in Serotonin transporter using serotonin uptake assay in rat midbrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  112nMAssay Description:Ratio of Ki value towards Serotonin transporter to that of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035726(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataKi:  129nMAssay Description:Inhibition of [3H]- 5-HT uptake in Serotonin transporter using serotonin uptake assay in rat midbrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataKi:  161nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataKi:  173nMAssay Description:Ratio of Ki value towards Serotonin transporter to that of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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