TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.410nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...More data for this Ligand-Target Pair
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.840nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of [3H]PDBu binding to C1b domain of protein kinase C delta with phosphatidylserineMore data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity for isolated C1b domain of protein kinase C-deltaMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 0.960nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.15nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity for isolated C1b domain of protein kinase C-deltaMore data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of [3H]-PDBu binding to C1b domain of protein kinase C deltaMore data for this Ligand-Target Pair
Affinity DataKi: 1.21nMAssay Description:Binding affinity to mouse wildtype PKCdelta C1a expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity to PKCdeltaC1b in presence of phospholipidMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]PDBu from recombinant human GFP-tagged RasGRP3 expressed in Escherichia coli BL21 after 5 mins by scintillation counting analysis...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Instituto Nacional De Tecnolog£A Industrial
Curated by ChEMBL
Instituto Nacional De Tecnolog£A Industrial
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-PDBu from recombinant human PKCepsilon by scintillation counter methodMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.07nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.07nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.13nMAssay Description:Displacement of [3H]PDBu from mouse wild type C1b domain of PKCdelta expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Instituto Nacional De Tecnolog£A Industrial
Curated by ChEMBL
Instituto Nacional De Tecnolog£A Industrial
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]PDBu from recombinant human PKC-epsilon after 5 mins by scintillation counting analysis in presence of phosphatidylserineMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 2.22nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.45nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.45nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Instituto Nacional De Tecnolog£A Industrial
Curated by ChEMBL
Instituto Nacional De Tecnolog£A Industrial
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCepsilon expressed in baculovirus expression system after 5 mins by scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 2.66nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.66nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
National Institute Of Industrial Technology
Curated by ChEMBL
National Institute Of Industrial Technology
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair