Found 7 Enz. Inhib. hit(s) with Target = 'Ras guanyl-releasing protein 3' and Ligand = 'BDBM50280749' TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 6.09E+3nMAssay Description:Activation of RasGRP3 in human Ramos cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 1.83E+3nMAssay Description:Activation of GFP-tagged RasGRP3 (unknown origin) expressed in HEK293 cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 4.66E+3nMAssay Description:Activation of GFP-tagged RasGRP3 (unknown origin) expressed in HEK293 cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 2.98E+3nMAssay Description:Activation of GFP-tagged RasGRP3 (unknown origin) expressed in human LNCAP cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot metho...More data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 860nMAssay Description:Activation of RasGRP3 in human Ramos cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
TargetRas guanyl-releasing protein 3(Homo sapiens (Human))
Seoul National University
Curated by ChEMBL
Seoul National University
Curated by ChEMBL
Affinity DataEC50: 640nMAssay Description:Activation of GFP-tagged RasGRP3 (unknown origin) expressed in human LNCAP cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
