Compile Data Set for Download or QSAR
maximum 50k data
Found 319 with Last Name = 'perez' and Initial = 'jr'
TargetD(2) dopamine receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.0890nMAssay Description:Displacement of [3H]Spiperone from human recombinant dopamine D2S receptor expressed in CHO cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50435127(CHEMBL2392022)
Affinity DataKi:  0.120nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 2 in human KAN-TS cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM85035(CAS_65154-06-5 | PAF | bloodplatelet-activatingfac...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]PAF from platelet activating factor receptor in human platelets after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataKi:  0.210nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 1 in human SK-N-MC cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50156454(CHEMBL264100 | des-Arg10-Kallidin)
Affinity DataKi:  0.220nMAssay Description:Displacement of [3H](Des-Arg10)-Kallidin from bradykinin B1 receptor in human IMR90 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50049949((BK) H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH | (b...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]Bradykinin from human recombinant bradykinin B2 receptor expressed in CHEM1 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM22567(3H]pyrilamine | CHEMBL511 | Dorantamin | Mepyramin...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in CHOK1 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetGlucocorticoid receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]Dexamethasone from glucocorticoid receptor in human HeLaS3 cells after 2 hrsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]GR65630 from human recombinant 5HT3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50435126(CHEMBL2392023)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]Substance P from human recombinant substance P receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50435128(CHEMBL2391908)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]CGP54626 from human recombinant GABAB1A receptor expressed in CHO cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]Mibolerone from rat recombinant androgen receptor expressed in Escherichia coli after 4 hrsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]Haloperidol from sigma 1 receptor in human jurkat cells after 4 hrsMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM22568(1-cyano-3-{2-[({2-[(diaminomethylidene)amino]-1,3-...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]Aminopotentidine from human recombinant histamine H2 receptor expressed in CHOK1 cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50435127(CHEMBL2392022)
Affinity DataIC50:  0.210nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 2 in human KAN-TS cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50015490(CHEMBL438945 | H-YPSKPDNPGEDAPAEDMARYYSALRHYINLITR...)
Affinity DataIC50:  0.220nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 1 in human SK-N-MC cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataIC50:  0.25nMAssay Description:Displacement of [3H]Spiperone from human recombinant dopamine D2S receptor expressed in CHO cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM85035(CAS_65154-06-5 | PAF | bloodplatelet-activatingfac...)
Affinity DataIC50:  0.280nMAssay Description:Displacement of [3H]PAF from platelet activating factor receptor in human platelets after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50156454(CHEMBL264100 | des-Arg10-Kallidin)
Affinity DataIC50:  0.870nMAssay Description:Displacement of [3H](Des-Arg10)-Kallidin from bradykinin B1 receptor in human IMR90 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50049949((BK) H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH | (b...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [3H]Bradykinin from human recombinant bradykinin B2 receptor expressed in CHEM1 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM22567(3H]pyrilamine | CHEMBL511 | Dorantamin | Mepyramin...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in CHOK1 cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSubstance-P receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50435126(CHEMBL2392023)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]Substance P from human recombinant substance P receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [3H]Dexamethasone from glucocorticoid receptor in human HeLaS3 cells after 2 hrsMore data for this Ligand-Target Pair
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069751(CHEMBL2356114)
Affinity DataIC50:  5nMAssay Description:Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069751(CHEMBL2356114)
Affinity DataIC50:  5nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in uptake of [3H]CE from [3H]CE-HDL by by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid type B receptor subunit 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM50435128(CHEMBL2391908)
Affinity DataIC50:  6.40nMAssay Description:Displacement of [3H]CGP54626 from human recombinant GABAB1A receptor expressed in CHO cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataIC50:  6.5nMAssay Description:Displacement of [3H]Mibolerone from rat recombinant androgen receptor expressed in Escherichia coli after 4 hrsMore data for this Ligand-Target Pair
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandPNGBDBM113784(2-(4-Chlorophenyl)-2-(6-(trifluoromethyl)pyridin-2...)
Affinity DataIC50:  10nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandPNGBDBM113783(2-(4-Chlorophenyl)-2-(3-chloropyridin-2-yl) aceton...)
Affinity DataIC50:  10nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandPNGBDBM113799(2-(4-Chloro-2-fluorophenyl)-2-(5-(trifluoromethyl)...)
Affinity DataIC50:  10nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM82561(CAS_40796-97-2 | TROPANYL 3,5-DICHLOROBENZOATE | T...)
Affinity DataIC50:  11nMAssay Description:Displacement of [3H]GR65630 from human recombinant 5HT3 receptor expressed in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069751(CHEMBL2356114)
Affinity DataIC50:  17nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandPNGBDBM113772(2-(4-Fluorophenyl)-2-(6-(trifluoromethyl)pyridin-2...)
Affinity DataIC50:  20nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  21nMAssay Description:Displacement of [3H]Haloperidol from sigma 1 receptor in human jurkat cells after 4 hrsMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Broad Institute Of Mit And Harvard

Curated by ChEMBL
LigandPNGBDBM22568(1-cyano-3-{2-[({2-[(diaminomethylidene)amino]-1,3-...)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I]Aminopotentidine from human recombinant histamine H2 receptor expressed in CHOK1 cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50088281(CHEMBL3427475)
Affinity DataIC50:  23nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50088195(CHEMBL3427497)
Affinity DataIC50:  26nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50088267(CHEMBL3427489)
Affinity DataIC50:  27nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandPNGBDBM113771(2‐(4‐chlorophenyl)‐2‐(6...)
Affinity DataIC50:  40nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069719(CHEMBL2358771)
Affinity DataIC50:  54nMAssay Description:Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50088283(CHEMBL1478888)
Affinity DataIC50:  55nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandPNGBDBM113781(2-(4-Chloro-2-fluorophenyl)-2-(6-chloropyridin-2-y...)
Affinity DataIC50:  60nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069697(CHEMBL2356172)
Affinity DataIC50:  60nMAssay Description:Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandPNGBDBM113777(2-(6-Chloropyridin-2-yl)-2-(4-fluorophenyl)acetoni...)
Affinity DataIC50:  70nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50069714(CHEMBL2356554)
Affinity DataIC50:  92nMAssay Description:Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50088257(CHEMBL1612527)
Affinity DataIC50:  110nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandPNGBDBM113798(6-((4-Chloro-2-fluorophenyl)(cyano)methyl) picolin...)
Affinity DataIC50:  110nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcyl-homoserine lactone acylase PvdQ [A190E,F674L](Pseudomonas aeruginosa)
The Broad Institute , Cambridge, Massachusetts 02142, United States

LigandPNGBDBM113794(6-(Cyano(4-fluorophenyl)methyl)-3-methylpicolinoni...)
Affinity DataIC50:  130nMAssay Description:The assay was performed with nine compound concentrations that ranged from 3 nM to 19.5 µM with PvdQ concentration of 20 nM. The positive contro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50088268(CHEMBL3427488)
Affinity DataIC50:  130nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetScavenger receptor class B member 1(Mus musculus)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50088282(CHEMBL3427474)
Affinity DataIC50:  130nMAssay Description:Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 319 total ) | Next | Last >>
Jump to: