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Found 35 with Last Name = 'pisaneschi' and Initial = 'f'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326519((E)-N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-...)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Department Of Organic Chemistry Ugo Schiff University Of Firenze Via Della Lastruccia 13

Curated by ChEMBL
LigandPNGBDBM50237601(CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...)
Affinity DataIC50:  0.110nMAssay Description:Displacement of [125I]Echistatin from human placental integrin alpha-V-beta-5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Department Of Organic Chemistry Ugo Schiff University Of Firenze Via Della Lastruccia 13

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [125I]Echistatin from human placental integrin alpha-V-beta-5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326514((E)-4-(Methylamino)-but-2-enoic acid [4-(3-chloro-...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326513((E)-4-Methylamino-but-2-enoicacid[4-(3-chloro-4-fl...)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326517((E)-4-[(4-Fluorobenzyl)methylamino]-but-2-enoic ac...)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326518((E)-4-[(2-Fluoroethyl)methylamino]-but-2-enoic aci...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM3303(4-Anilinoquinazoline deriv. 54 | 4-N-(3-bromopheny...)
Affinity DataIC50:  0.810nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-enolase(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50590126(CHEMBL5185604)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of ENO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326516((E)-4-{[1-(2-Fluoroethyl)-1H-[1,2,3]triazol-4-ylme...)
Affinity DataIC50:  1.81nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326515((E)-N-[4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-...)
Affinity DataIC50:  4.05nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326514((E)-4-(Methylamino)-but-2-enoic acid [4-(3-chloro-...)
Affinity DataIC50:  5.35nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-enolase(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50590127(CHEMBL5187779)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of ENO1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)
Affinity DataIC50:  8.02nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326513((E)-4-Methylamino-but-2-enoicacid[4-(3-chloro-4-fl...)
Affinity DataIC50:  8.12nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Department Of Organic Chemistry Ugo Schiff University Of Firenze Via Della Lastruccia 13

Curated by ChEMBL
LigandPNGBDBM50376405(CHEMBL408195)
Affinity DataIC50:  14.3nMAssay Description:Displacement of [125I]Echistatin from human placental integrin alpha-V-beta-5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326517((E)-4-[(4-Fluorobenzyl)methylamino]-but-2-enoic ac...)
Affinity DataIC50:  16.5nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Department Of Organic Chemistry Ugo Schiff University Of Firenze Via Della Lastruccia 13

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  18.9nMAssay Description:Displacement of [125I]echistatin from human placental integrin alphaVbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326516((E)-4-{[1-(2-Fluoroethyl)-1H-[1,2,3]triazol-4-ylme...)
Affinity DataIC50:  22.0nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326518((E)-4-[(2-Fluoroethyl)methylamino]-but-2-enoic aci...)
Affinity DataIC50:  23.0nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Department Of Organic Chemistry Ugo Schiff University Of Firenze Via Della Lastruccia 13

Curated by ChEMBL
LigandPNGBDBM50376405(CHEMBL408195)
Affinity DataIC50:  34.4nMAssay Description:Displacement of [125I]echistatin from human placental integrin alphaVbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-enolase(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM204924(SF2312)
Affinity DataIC50:  37.9nMpH: 7.4Assay Description:Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-enolase(Homo sapiens (Human))
University of Texas M. D. Anderson Cancer Center

LigandPNGBDBM204924(SF2312)
Affinity DataIC50:  42.5nMpH: 7.4Assay Description:Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...More data for this Ligand-Target Pair
TargetAlpha-enolase(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM204923(phosphonoacetohydroxamate (PhAH))
Affinity DataIC50:  51nMAssay Description:Inhibition of ENO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-enolase(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM204923(phosphonoacetohydroxamate (PhAH))
Affinity DataIC50:  53.2nMpH: 7.4Assay Description:Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326519((E)-N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-...)
Affinity DataIC50:  60.2nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-enolase(Homo sapiens (Human))
University of Texas M. D. Anderson Cancer Center

LigandPNGBDBM204923(phosphonoacetohydroxamate (PhAH))
Affinity DataIC50:  62.3nMpH: 7.4Assay Description:Enolase activity was measured by two different methods: a fluorometric NADH-linked assay or adirect spectrophotometric assay via formation of PEP. In...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Department Of Organic Chemistry Ugo Schiff University Of Firenze Via Della Lastruccia 13

Curated by ChEMBL
LigandPNGBDBM50237601(CHEMBL411941 | CycloRGDfV | [(2S,5R,8S,11S)-5-Benz...)
Affinity DataIC50:  196nMAssay Description:Displacement of [125I]echistatin from human placental integrin alphaVbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM50326515((E)-N-[4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Imperial College

Curated by ChEMBL
LigandPNGBDBM3303(4-Anilinoquinazoline deriv. 54 | 4-N-(3-bromopheny...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Department Of Organic Chemistry Ugo Schiff University Of Firenze Via Della Lastruccia 13

Curated by ChEMBL
LigandPNGBDBM50376404(CHEMBL265445)
Affinity DataIC50:  2.15E+3nMAssay Description:Displacement of [125I]echistatin from human placental integrin alphaVbeta3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-enolase(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50590125(CHEMBL5193347)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of ENO1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-enolase(Homo sapiens (Human))
University Of Texas Md Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50543109(CHEMBL4647387)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of ENO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Department Of Organic Chemistry Ugo Schiff University Of Firenze Via Della Lastruccia 13

Curated by ChEMBL
LigandPNGBDBM50376404(CHEMBL265445)
Affinity DataIC50:  7.96E+3nMAssay Description:Displacement of [125I]Echistatin from human placental integrin alpha-V-beta-5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed