Found 114 with Last Name = 'ramachandran' and Initial = 'v' 
Affinity DataKi: 6.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortex using [125]-(R)-DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 7.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortex using [125]-(R)-DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortex using [125]-(R)-DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor from rat frontal cortex using [125]-(R)-DOI as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Mycobacterium tuberculosis InhA using NADH and dodecyl coA substrate by LC-MS/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bugworks Research
US Patent
Bugworks Research
US Patent
Affinity DataIC50: 150nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
Affinity DataIC50: 233nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 342nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 626nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of Mycobacterium tuberculosis InhA using dodecyl coA as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 703nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human recombinant CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.49E+3nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 3.85E+3nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 3.91E+3nMAssay Description:Inhibition of human recombinant CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.04E+3nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 5.24E+3nMAssay Description:Inhibition of human recombinant CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.87E+3nMpH: 7.5 T: 2°CAssay Description:The test compounds and enzyme were mixed in buffer, and the substrate and [gamma-33P] ATP/ATP were added to the mixture to initiate the reaction. Aft...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of adenosine A1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of adenosine A1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of adenosine A1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of adenosine A1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.56E+3nMAssay Description:Inhibition of human recombinant CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human recombinant CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of human recombinant CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bugworks Research
US Patent
Bugworks Research
US Patent
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human ERG by medium-throughput electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of human recombinant CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of human recombinant CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of human recombinant CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of human recombinant CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of human recombinant CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of human recombinant CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of human recombinant CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
